Cooper JF - Search Results

1

Genetics: A cross-kingdom evolutionary handoff.

Cooper JF, Wang X, Burton NO. Cooper JF, et al. Curr Biol. 2022 Nov 21;32(22):R1267-R1269. doi: 10.1016/j.cub.2022.09.057. Curr Biol. 2022. PMID: 36413968 Free article.

2

Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways.

Wu Z, Senchuk MM, Dues DJ, Johnson BK, Cooper JF, Lew L, Machiela E, Schaar CE, DeJonge H, Blackwell TK, Van Raamsdonk JM. Wu Z, et al. Among authors: cooper jf. BMC Biol. 2018 Dec 18;16(1):147. doi: 10.1186/s12915-018-0615-3. BMC Biol. 2018. PMID: 30563508 Free PMC article.

3

Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson's disease models.

Cooper JF, Machiela E, Dues DJ, Spielbauer KK, Senchuk MM, Van Raamsdonk JM. Cooper JF, et al. Sci Rep. 2017 Nov 27;7(1):16441. doi: 10.1038/s41598-017-16637-2. Sci Rep. 2017. PMID: 29180793 Free PMC article.

4

Disruption of mitochondrial dynamics increases stress resistance through activation of multiple stress response pathways.

Machiela E, Liontis T, Dues DJ, Rudich PD, Traa A, Wyman L, Kaufman C, Cooper JF, Lew L, Nadarajan S, Senchuk MM, Van Raamsdonk JM. Machiela E, et al. Among authors: cooper jf. FASEB J. 2020 Jun;34(6):8475-8492. doi: 10.1096/fj.201903235R. Epub 2020 May 8. FASEB J. 2020. PMID: 32385951 Free PMC article.

5

Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synuclein.

Tyson T, Senchuk M, Cooper JF, George S, Van Raamsdonk JM, Brundin P. Tyson T, et al. Among authors: cooper jf. Sci Rep. 2017 Aug 8;7(1):7506. doi: 10.1038/s41598-017-07383-6. Sci Rep. 2017. PMID: 28790319 Free PMC article.

6

Mitochondrial and cytoplasmic ROS have opposing effects on lifespan.

Schaar CE, Dues DJ, Spielbauer KK, Machiela E, Cooper JF, Senchuk M, Hekimi S, Van Raamsdonk JM. Schaar CE, et al. Among authors: cooper jf. PLoS Genet. 2015 Feb 11;11(2):e1004972. doi: 10.1371/journal.pgen.1004972. eCollection 2015 Feb. PLoS Genet. 2015. PMID: 25671321 Free PMC article.

7

Modeling Parkinson's Disease in C. elegans.

Cooper JF, Van Raamsdonk JM. Cooper JF, et al. J Parkinsons Dis. 2018;8(1):17-32. doi: 10.3233/JPD-171258. J Parkinsons Dis. 2018. PMID: 29480229 Free PMC article. Review.

8

α-synuclein expression from a single copy transgene increases sensitivity to stress and accelerates neuronal loss in genetic models of Parkinson's disease.

Cooper JF, Spielbauer KK, Senchuk MM, Nadarajan S, Colaiácovo MP, Van Raamsdonk JM. Cooper JF, et al. Exp Neurol. 2018 Dec;310:58-69. doi: 10.1016/j.expneurol.2018.09.001. Epub 2018 Sep 5. Exp Neurol. 2018. PMID: 30194957 Free PMC article.

9

Stress increases in exopher-mediated neuronal extrusion require lipid biosynthesis, FGF, and EGF RAS/MAPK signaling.

Cooper JF, Guasp RJ, Arnold ML, Grant BD, Driscoll M. Cooper JF, et al. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2101410118. doi: 10.1073/pnas.2101410118. Proc Natl Acad Sci U S A. 2021. PMID: 34475208 Free PMC article.

10

Delaying aging is neuroprotective in Parkinson's disease: a genetic analysis in C. elegans models.

Cooper JF, Dues DJ, Spielbauer KK, Machiela E, Senchuk MM, Van Raamsdonk JM. Cooper JF, et al. NPJ Parkinsons Dis. 2015 Nov 19;1:15022. doi: 10.1038/npjparkd.2015.22. eCollection 2015. NPJ Parkinsons Dis. 2015. PMID: 28725688 Free PMC article.

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