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Two Transient Receptor Potential Channels at Focal Adhesions.
Mitsou I, Carlson CR, Multhaupt HAB, Brakebusch C, Couchman JR. Mitsou I, et al. J Histochem Cytochem. 2023 Sep;71(9):495-508. doi: 10.1369/00221554231194119. Epub 2023 Aug 18. J Histochem Cytochem. 2023. PMID: 37596792
Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance.
Socodato R, Almeida TO, Portugal CC, Santos ECS, Tedim-Moreira J, Galvão-Ferreira J, Canedo T, Baptista FI, Magalhães A, Ambrósio AF, Brakebusch C, Rubinstein B, Moreira IS, Summavielle T, Pinto IM, Relvas JB. Socodato R, et al. Cell Rep. 2023 Dec 26;42(12):113447. doi: 10.1016/j.celrep.2023.113447. Epub 2023 Nov 18. Cell Rep. 2023. PMID: 37980559 Free article.
RhoB promotes Salmonella survival by regulating autophagy.
Kirchenwitz M, Halfen J, von Peinen K, Prettin S, Kollasser J, Zur Lage S, Blankenfeldt W, Brakebusch C, Rottner K, Steffen A, Stradal TEB. Kirchenwitz M, et al. Eur J Cell Biol. 2023 Dec;102(4):151358. doi: 10.1016/j.ejcb.2023.151358. Epub 2023 Aug 30. Eur J Cell Biol. 2023. PMID: 37703749 Free article.
Rac1 promotes kidney collecting duct repair by mechanically coupling cell morphology to mitotic entry.
Bock F, Dong X, Li S, Viquez OM, Sha E, Tantengco M, Hennen EM, Plosa E, Ramezani A, Brown KL, Whang YM, Terker AS, Arroyo JP, Harrison DG, Fogo A, Brakebusch CH, Pozzi A, Zent R. Bock F, et al. Among authors: brakebusch ch. Sci Adv. 2024 Feb 9;10(6):eadi7840. doi: 10.1126/sciadv.adi7840. Epub 2024 Feb 7. Sci Adv. 2024. PMID: 38324689 Free PMC article.
The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells.
Vadakumchery A, Faraidun H, Ayoubi OE, Outaleb I, Schmid V, Abdelrasoul H, Amendt T, Khadour A, Setz C, Göhring K, Lodd K, Hitzing C, Alkhatib A, Bilal M, Benckendorff J, Al Shugri AK, Brakebusch CH, Engels N, Datta M, Hobeika E, Alsadeq A, Jumaa H. Vadakumchery A, et al. Among authors: brakebusch ch. Front Immunol. 2022 Mar 15;13:842340. doi: 10.3389/fimmu.2022.842340. eCollection 2022. Front Immunol. 2022. PMID: 35371049 Free PMC article.
Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity.
Bock F, Elias BC, Dong X, Parekh DV, Mernaugh G, Viquez OM, Hassan A, Amara VR, Liu J, Brown KL, Terker AS, Chiusa M, Gewin LS, Fogo AB, Brakebusch CH, Pozzi A, Zent R. Bock F, et al. Among authors: brakebusch ch. J Cell Biol. 2021 Nov 1;220(11):e202103080. doi: 10.1083/jcb.202103080. Epub 2021 Oct 14. J Cell Biol. 2021. PMID: 34647970 Free PMC article.
Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice.
López-Posadas R, Fastancz P, Martínez-Sánchez LDC, Panteleev-Ivlev J, Thonn V, Kisseleva T, Becker LS, Schulz-Kuhnt A, Zundler S, Wirtz S, Atreya R, Carlé B, Friedrich O, Schürmann S, Waldner MJ, Neufert C, Brakebusch CH, Bergö MO, Neurath MF, Atreya I. López-Posadas R, et al. Among authors: brakebusch ch. Gastroenterology. 2019 Nov;157(5):1293-1309. doi: 10.1053/j.gastro.2019.07.007. Epub 2019 Jul 11. Gastroenterology. 2019. PMID: 31302143 Free article.
Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin.
Woodham EF, Paul NR, Tyrrell B, Spence HJ, Swaminathan K, Scribner MR, Giampazolias E, Hedley A, Clark W, Kage F, Marston DJ, Hahn KM, Tait SW, Larue L, Brakebusch CH, Insall RH, Machesky LM. Woodham EF, et al. Among authors: brakebusch ch. Curr Biol. 2017 Mar 6;27(5):624-637. doi: 10.1016/j.cub.2017.01.033. Epub 2017 Feb 23. Curr Biol. 2017. PMID: 28238662 Free PMC article.
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