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HER2 Copy Number and Resistance Mechanisms in Patients with HER2-positive Advanced Gastric Cancer Receiving Initial Trastuzumab-based Therapy in JACOB Trial.
Pietrantonio F, Manca P, Bellomo SE, Corso S, Raimondi A, Berrino E, Morano F, Migliore C, Niger M, Castagnoli L, Pupa SM, Marchiò C, Di Bartolomeo M, Restuccia E, Lambertini C, Tabernero J, Giordano S. Pietrantonio F, et al. Among authors: pupa sm. Clin Cancer Res. 2023 Feb 1;29(3):571-580. doi: 10.1158/1078-0432.CCR-22-2533. Clin Cancer Res. 2023. PMID: 36413222 Free PMC article.
A limited autoimmunity to p185neu elicited by DNA and allogeneic cell vaccine hampers the progression of preneoplastic lesions in HER-2/NEU transgenic mice.
Lo Iacono M, Cavallo F, Quaglino E, Rolla S, Iezzi M, Pupa SM, De Giovanni C, Lollini PL, Musiani P, Forni G, Calogero RA. Lo Iacono M, et al. Among authors: pupa sm. Int J Immunopathol Pharmacol. 2005 Apr-Jun;18(2):351-63. doi: 10.1177/039463200501800217. Int J Immunopathol Pharmacol. 2005. PMID: 15888257 Free article.
Identification of relevant conformational epitopes on the HER2 oncoprotein by using Large Fragment Phage Display (LFPD).
Gabrielli F, Salvi R, Garulli C, Kalogris C, Arima S, Tardella L, Monaci P, Pupa SM, Tagliabue E, Montani M, Quaglino E, Stramucci L, Curcio C, Marchini C, Amici A. Gabrielli F, et al. Among authors: pupa sm. PLoS One. 2013;8(3):e58358. doi: 10.1371/journal.pone.0058358. Epub 2013 Mar 28. PLoS One. 2013. PMID: 23555577 Free PMC article.
Serological identification of HSP105 as a novel non-Hodgkin lymphoma therapeutic target.
Zappasodi R, Bongarzone I, Ghedini GC, Castagnoli L, Cabras AD, Messina A, Tortoreto M, Tripodo C, Magni M, Carlo-Stella C, Gianni AM, Pupa SM, Di Nicola M. Zappasodi R, et al. Among authors: pupa sm. Blood. 2011 Oct 20;118(16):4421-30. doi: 10.1182/blood-2011-06-364570. Epub 2011 Aug 22. Blood. 2011. PMID: 21860023 Free article.
Activated d16HER2 homodimers and SRC kinase mediate optimal efficacy for trastuzumab.
Castagnoli L, Iezzi M, Ghedini GC, Ciravolo V, Marzano G, Lamolinara A, Zappasodi R, Gasparini P, Campiglio M, Amici A, Chiodoni C, Palladini A, Lollini PL, Triulzi T, Menard S, Nanni P, Tagliabue E, Pupa SM. Castagnoli L, et al. Among authors: pupa sm. Cancer Res. 2014 Nov 1;74(21):6248-59. doi: 10.1158/0008-5472.CAN-14-0983. Epub 2014 Aug 27. Cancer Res. 2014. PMID: 25164009
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