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The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells.
Borges da Silva H, Beura LK, Wang H, Hanse EA, Gore R, Scott MC, Walsh DA, Block KE, Fonseca R, Yan Y, Hippen KL, Blazar BR, Masopust D, Kelekar A, Vulchanova L, Hogquist KA, Jameson SC. Borges da Silva H, et al. Among authors: block ke. Nature. 2018 Jul;559(7713):264-268. doi: 10.1038/s41586-018-0282-0. Epub 2018 Jul 4. Nature. 2018. PMID: 29973721 Free PMC article.
Mice with diverse microbial exposure histories as a model for preclinical vaccine testing.
Fiege JK, Block KE, Pierson MJ, Nanda H, Shepherd FK, Mickelson CK, Stolley JM, Matchett WE, Wijeyesinghe S, Meyerholz DK, Vezys V, Shen SS, Hamilton SE, Masopust D, Langlois RA. Fiege JK, et al. Among authors: block ke. Cell Host Microbe. 2021 Dec 8;29(12):1815-1827.e6. doi: 10.1016/j.chom.2021.10.001. Epub 2021 Nov 2. Cell Host Microbe. 2021. PMID: 34731647 Free PMC article.
CD8+ T cell self-tolerance permits responsiveness but limits tissue damage.
Truckenbrod EN, Burrack KS, Knutson TP, Borges da Silva H, Block KE, O'Flanagan SD, Stagliano KR, Hurwitz AA, Fulton RB, Renkema KR, Jameson SC. Truckenbrod EN, et al. Among authors: block ke. Elife. 2021 Apr 30;10:e65615. doi: 10.7554/eLife.65615. Elife. 2021. PMID: 33929324 Free PMC article.
12 results