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Lassa antiviral LHF-535 protects guinea pigs from lethal challenge.
Sci Rep. 2022 Nov 19;12(1):19911. doi: 10.1038/s41598-022-23760-2.
Sci Rep. 2022.
PMID: 36402782
Free PMC article.
A potent Lassa virus antiviral targets an arenavirus virulence determinant.
Madu IG, Files M, Gharaibeh DN, Moore AL, Jung KH, Gowen BB, Dai D, Jones KF, Tyavanagimatt SR, Burgeson JR, Korth MJ, Bedard KM, Iadonato SP, Amberg SM.
Madu IG, et al.
PLoS Pathog. 2018 Dec 21;14(12):e1007439. doi: 10.1371/journal.ppat.1007439. eCollection 2018 Dec.
PLoS Pathog. 2018.
PMID: 30576397
Free PMC article.
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A Novel Class of HIV-1 Antiviral Agents Targeting HIV via a SUMOylation-Dependent Mechanism.
Madu IG, Li S, Li B, Li H, Chang T, Li YJ, Vega R, Rossi J, Yee JK, Zaia J, Chen Y.
Madu IG, et al.
Sci Rep. 2015 Dec 8;5:17808. doi: 10.1038/srep17808.
Sci Rep. 2015.
PMID: 26643614
Free PMC article.
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Identification and characterization of a new chemotype of noncovalent SENP inhibitors.
Madu IG, Namanja AT, Su Y, Wong S, Li YJ, Chen Y.
Madu IG, et al.
ACS Chem Biol. 2013 Jul 19;8(7):1435-41. doi: 10.1021/cb400177q. Epub 2013 May 1.
ACS Chem Biol. 2013.
PMID: 23614497
Free PMC article.
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Assays for investigating deSUMOylation enzymes.
Madu IG, Chen Y.
Madu IG, et al.
Curr Protoc Mol Biol. 2012 Jul;Chapter 10:Unit10.30. doi: 10.1002/0471142727.mb1030s99.
Curr Protoc Mol Biol. 2012.
PMID: 22870856
Free PMC article.
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SARS-coronavirus spike S2 domain flanked by cysteine residues C822 and C833 is important for activation of membrane fusion.
Madu IG, Belouzard S, Whittaker GR.
Madu IG, et al.
Virology. 2009 Oct 25;393(2):265-71. doi: 10.1016/j.virol.2009.07.038. Epub 2009 Aug 29.
Virology. 2009.
PMID: 19717178
Free PMC article.
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Characterization of a highly conserved domain within the severe acute respiratory syndrome coronavirus spike protein S2 domain with characteristics of a viral fusion peptide.
Madu IG, Roth SL, Belouzard S, Whittaker GR.
Madu IG, et al.
J Virol. 2009 Aug;83(15):7411-21. doi: 10.1128/JVI.00079-09. Epub 2009 May 13.
J Virol. 2009.
PMID: 19439480
Free PMC article.
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Heparan sulfate is a selective attachment factor for the avian coronavirus infectious bronchitis virus Beaudette.
Madu IG, Chu VC, Lee H, Regan AD, Bauman BE, Whittaker GR.
Madu IG, et al.
Avian Dis. 2007 Mar;51(1):45-51. doi: 10.1637/0005-2086(2007)051[0045:HSIASA]2.0.CO;2.
Avian Dis. 2007.
PMID: 17461266
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