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Lassa antiviral LHF-535 protects guinea pigs from lethal challenge.
Cashman KA, Wilkinson ER, Posakony J, Madu IG, Tarcha EJ, Lustig KH, Korth MJ, Bedard KM, Amberg SM. Cashman KA, et al. Among authors: madu ig. Sci Rep. 2022 Nov 19;12(1):19911. doi: 10.1038/s41598-022-23760-2. Sci Rep. 2022. PMID: 36402782 Free PMC article.
A potent Lassa virus antiviral targets an arenavirus virulence determinant.
Madu IG, Files M, Gharaibeh DN, Moore AL, Jung KH, Gowen BB, Dai D, Jones KF, Tyavanagimatt SR, Burgeson JR, Korth MJ, Bedard KM, Iadonato SP, Amberg SM. Madu IG, et al. PLoS Pathog. 2018 Dec 21;14(12):e1007439. doi: 10.1371/journal.ppat.1007439. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30576397 Free PMC article.
Assays for investigating deSUMOylation enzymes.
Madu IG, Chen Y. Madu IG, et al. Curr Protoc Mol Biol. 2012 Jul;Chapter 10:Unit10.30. doi: 10.1002/0471142727.mb1030s99. Curr Protoc Mol Biol. 2012. PMID: 22870856 Free PMC article.