Mahameed M - Search Results

1

An mTORC1 to HRI signaling axis promotes cytotoxicity of proteasome inhibitors in multiple myeloma.

Darawshi O, Muz B, Naamat SG, Praveen B, Mahameed M, Goldberg K, Dipta P, Shmuel M, Forno F, Boukeileh S, Pahima H, Hermann J, Raab MS, Poos AM, Weinhold N, Rosenbluh C, Gatt ME, Palm W, Azab AK, Tirosh B. Darawshi O, et al. Among authors: mahameed m. Cell Death Dis. 2022 Nov 18;13(11):969. doi: 10.1038/s41419-022-05421-4. Cell Death Dis. 2022. PMID: 36400754 Free PMC article.

2

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors.

Mahameed M, Wilhelm T, Darawshi O, Obiedat A, Tommy WS, Chintha C, Schubert T, Samali A, Chevet E, Eriksson LA, Huber M, Tirosh B. Mahameed M, et al. Cell Death Dis. 2019 Apr 1;10(4):300. doi: 10.1038/s41419-019-1523-3. Cell Death Dis. 2019. PMID: 30931942 Free PMC article.

3

The integrated stress response promotes B7H6 expression.

Obiedat A, Charpak-Amikam Y, Tai-Schmiedel J, Seidel E, Mahameed M, Avril T, Stern-Ginossar N, Springuel L, Bolsée J, Gilham DE, Dipta P, Shmuel M, Chevet E, Mandelboim O, Tirosh B. Obiedat A, et al. Among authors: mahameed m. J Mol Med (Berl). 2020 Jan;98(1):135-148. doi: 10.1007/s00109-019-01859-w. Epub 2019 Dec 14. J Mol Med (Berl). 2020. PMID: 31838577 Free PMC article.

4

Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy.

Mahameed M, Boukeileh S, Obiedat A, Darawshi O, Dipta P, Rimon A, McLennan G, Fassler R, Reichmann D, Karni R, Preisinger C, Wilhelm T, Huber M, Tirosh B. Mahameed M, et al. Nat Commun. 2020 Mar 11;11(1):1304. doi: 10.1038/s41467-020-15067-5. Nat Commun. 2020. PMID: 32161259 Free PMC article.

5

Aripiprazole Cytotoxicity Coincides with Activation of the Unfolded Protein Response in Human Hepatic Cells.

Forno F, Maatuf Y, Boukeileh S, Dipta P, Mahameed M, Darawshi O, Ferreira V, Rada P, García-Martinez I, Gross E, Priel A, Valverde ÁM, Tirosh B. Forno F, et al. Among authors: mahameed m. J Pharmacol Exp Ther. 2020 Sep;374(3):452-461. doi: 10.1124/jpet.119.264481. Epub 2020 Jun 17. J Pharmacol Exp Ther. 2020. PMID: 32554435 Free article.

6

Endoplasmic Reticulum Homeostasis Regulates TLR4 Expression and Signaling in Mast Cells.

Boukeileh S, Darawshi O, Shmuel M, Mahameed M, Wilhelm T, Dipta P, Forno F, Praveen B, Huber M, Levi-Schaffer F, Tirosh B. Boukeileh S, et al. Among authors: mahameed m. Int J Mol Sci. 2022 Oct 5;23(19):11826. doi: 10.3390/ijms231911826. Int J Mol Sci. 2022. PMID: 36233127 Free PMC article.

7

Engineering CHO cells with an oncogenic KIT improves cells growth, resilience to stress, and productivity.

Mahameed M, Tirosh B. Mahameed M, et al. Biotechnol Bioeng. 2017 Nov;114(11):2560-2570. doi: 10.1002/bit.26356. Epub 2017 Sep 4. Biotechnol Bioeng. 2017. PMID: 28627778

8

Towards Enhancing Therapeutic Glycoprotein Bioproduction: Interventions in the PI3K/AKT/mTOR Pathway.

Mahameed M, Sulieman A, Alkam D, Tirosh B. Mahameed M, et al. Cell Struct Funct. 2019;44(2):75-83. doi: 10.1247/csf.19013. Cell Struct Funct. 2019. PMID: 31353334 Free article. Review.

9

Low concentrations of cadmium chloride promotes protein translation and improve cell line productivity.

Mahameed M, Obiedat A, Beck G, Johnson JC, Tirosh B. Mahameed M, et al. Biotechnol Bioeng. 2019 Mar;116(3):569-580. doi: 10.1002/bit.26888. Epub 2019 Jan 4. Biotechnol Bioeng. 2019. PMID: 30512193

10

Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation.

Weiss-Sadan T, Itzhak G, Kaschani F, Yu Z, Mahameed M, Anaki A, Ben-Nun Y, Merquiol E, Tirosh B, Kessler B, Kaiser M, Blum G. Weiss-Sadan T, et al. Among authors: mahameed m. Mol Cell Proteomics. 2019 Jul;18(7):1330-1344. doi: 10.1074/mcp.RA119.001392. Epub 2019 Apr 22. Mol Cell Proteomics. 2019. PMID: 31010818 Free PMC article.

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