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GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141.
Naesens L, Muppala S, Acharya D, Nemegeer J, Bogaert D, Lee JH, Staes K, Debacker V, De Bleser P, De Bruyne M, De Baere E, van Gent M, Liu G, Lambrecht BN, Staal J, Kerre T, Beyaert R, Maelfait J, Tavernier SJ, Gack MU, Haerynck F. Naesens L, et al. Among authors: staal j. Sci Immunol. 2022 Nov 25;7(77):eabq4531. doi: 10.1126/sciimmunol.abq4531. Epub 2022 Nov 18. Sci Immunol. 2022. PMID: 36399538 Free PMC article.
A two-step activation mechanism of MALT1 paracaspase.
Staal J, Beyaert R. Staal J, et al. J Mol Biol. 2012 May 25;419(1-2):1-3. doi: 10.1016/j.jmb.2012.03.006. Epub 2012 Mar 15. J Mol Biol. 2012. PMID: 22426126 Free article. No abstract available.
MALT1 is not alone after all: identification of novel paracaspases.
Hulpiau P, Driege Y, Staal J, Beyaert R. Hulpiau P, et al. Among authors: staal j. Cell Mol Life Sci. 2016 Mar;73(5):1103-16. doi: 10.1007/s00018-015-2041-9. Epub 2015 Sep 16. Cell Mol Life Sci. 2016. PMID: 26377317 Free PMC article.
265 results