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GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141.
Sci Immunol. 2022 Nov 25;7(77):eabq4531. doi: 10.1126/sciimmunol.abq4531. Epub 2022 Nov 18.
Sci Immunol. 2022.
PMID: 36399538
Free PMC article.
Tyramide Signal Amplification for the Immunofluorescent Staining of ZBP1-dependent Phosphorylation of RIPK3 and MLKL After HSV-1 Infection in Human Cells.
Nemegeer J, Lemeire K, Vandenabeele P, Maelfait J.
Nemegeer J, et al.
J Vis Exp. 2022 Oct 20;(188). doi: 10.3791/64332.
J Vis Exp. 2022.
PMID: 36342164
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Approaching or Decentering? Differential Neural Networks Underlying Experiential Emotion Regulation and Cognitive Defusion.
Wang Y, Vantieghem I, Dong D, Nemegeer J, De Mey J, Van Schuerbeek P, Marinazzo D, Vandekerckhove M.
Wang Y, et al. Among authors: nemegeer j.
Brain Sci. 2022 Sep 9;12(9):1215. doi: 10.3390/brainsci12091215.
Brain Sci. 2022.
PMID: 36138951
Free PMC article.
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ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation.
de Reuver R, Verdonck S, Dierick E, Nemegeer J, Hessmann E, Ahmad S, Jans M, Blancke G, Van Nieuwerburgh F, Botzki A, Vereecke L, van Loo G, Declercq W, Hur S, Vandenabeele P, Maelfait J.
de Reuver R, et al. Among authors: nemegeer j.
Nature. 2022 Jul;607(7920):784-789. doi: 10.1038/s41586-022-04974-w. Epub 2022 Jul 20.
Nature. 2022.
PMID: 35859175
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Mutations in RNU7-1 Weaken Secondary RNA Structure, Induce MCP-1 and CXCL10 in CSF, and Result in Aicardi-Goutières Syndrome with Severe End-Organ Involvement.
Naesens L, Nemegeer J, Roelens F, Vallaeys L, Meuwissen M, Janssens K, Verloo P, Ogunjimi B, Hemelsoet D; Program for Undiagnosed Rare Diseases (UD-PrOZA); Hoste L, Roels L, De Bruyne M, De Baere E, Van Dorpe J, Dendooven A, Sieben A, Rice GI, Kerre T, Beyaert R, Uggenti C, Crow YJ, Tavernier SJ, Maelfait J, Haerynck F.
Naesens L, et al. Among authors: nemegeer j.
J Clin Immunol. 2022 Jul;42(5):962-974. doi: 10.1007/s10875-022-01209-5. Epub 2022 Mar 23.
J Clin Immunol. 2022.
PMID: 35320431
Free PMC article.
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Viral manipulation of host cell necroptosis and pyroptosis.
Verdonck S, Nemegeer J, Vandenabeele P, Maelfait J.
Verdonck S, et al. Among authors: nemegeer j.
Trends Microbiol. 2022 Jun;30(6):593-605. doi: 10.1016/j.tim.2021.11.011. Epub 2021 Dec 18.
Trends Microbiol. 2022.
PMID: 34933805
Review.
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Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation.
Devos M, Tanghe G, Gilbert B, Dierick E, Verheirstraeten M, Nemegeer J, de Reuver R, Lefebvre S, De Munck J, Rehwinkel J, Vandenabeele P, Declercq W, Maelfait J.
Devos M, et al. Among authors: nemegeer j.
J Exp Med. 2020 Jul 6;217(7):e20191913. doi: 10.1084/jem.20191913.
J Exp Med. 2020.
PMID: 32315377
Free PMC article.
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