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GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141.
Naesens L, Muppala S, Acharya D, Nemegeer J, Bogaert D, Lee JH, Staes K, Debacker V, De Bleser P, De Bruyne M, De Baere E, van Gent M, Liu G, Lambrecht BN, Staal J, Kerre T, Beyaert R, Maelfait J, Tavernier SJ, Gack MU, Haerynck F. Naesens L, et al. Among authors: muppala s. Sci Immunol. 2022 Nov 25;7(77):eabq4531. doi: 10.1126/sciimmunol.abq4531. Epub 2022 Nov 18. Sci Immunol. 2022. PMID: 36399538 Free PMC article.
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication.
Serman T, Chiang C, Liu G, Sayyad Z, Pandey S, Volcic M, Lee H, Muppala S, Acharya D, Goins C, Stauffer SR, Sparrer KMJ, Gack MU. Serman T, et al. Among authors: muppala s. Cell Host Microbe. 2023 Aug 9;31(8):1317-1330.e10. doi: 10.1016/j.chom.2023.06.013. Epub 2023 Jul 20. Cell Host Microbe. 2023. PMID: 37478852
Myeloid-cell-specific role of Gasdermin D in promoting lung cancer progression in mice.
Traughber CA, Deshpande GM, Neupane K, Bhandari N, Khan MR, McMullen MR, Swaidani S, Opoku E, Muppala S, Smith JD, Nagy LE, Gulshan K. Traughber CA, et al. Among authors: muppala s. iScience. 2023 Jan 31;26(2):106076. doi: 10.1016/j.isci.2023.106076. eCollection 2023 Feb 17. iScience. 2023. PMID: 36844454 Free PMC article.
25 results