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Conformational states of the full-length glucagon receptor.
Yang L, Yang D, de Graaf C, Moeller A, West GM, Dharmarajan V, Wang C, Siu FY, Song G, Reedtz-Runge S, Pascal BD, Wu B, Potter CS, Zhou H, Griffin PR, Carragher B, Yang H, Wang MW, Stevens RC, Jiang H. Yang L, et al. Among authors: yang d, yang h. Nat Commun. 2015 Jul 31;6:7859. doi: 10.1038/ncomms8859. Nat Commun. 2015. PMID: 26227798 Free PMC article.
Structure of the full-length glucagon class B G-protein-coupled receptor.
Zhang H, Qiao A, Yang D, Yang L, Dai A, de Graaf C, Reedtz-Runge S, Dharmarajan V, Zhang H, Han GW, Grant TD, Sierra RG, Weierstall U, Nelson G, Liu W, Wu Y, Ma L, Cai X, Lin G, Wu X, Geng Z, Dong Y, Song G, Griffin PR, Lau J, Cherezov V, Yang H, Hanson MA, Stevens RC, Zhao Q, Jiang H, Wang MW, Wu B. Zhang H, et al. Among authors: yang d, yang l, yang h. Nature. 2017 Jun 8;546(7657):259-264. doi: 10.1038/nature22363. Epub 2017 May 17. Nature. 2017. PMID: 28514451 Free PMC article.
Structure of the glucagon receptor in complex with a glucagon analogue.
Zhang H, Qiao A, Yang L, Van Eps N, Frederiksen KS, Yang D, Dai A, Cai X, Zhang H, Yi C, Cao C, He L, Yang H, Lau J, Ernst OP, Hanson MA, Stevens RC, Wang MW, Reedtz-Runge S, Jiang H, Zhao Q, Wu B. Zhang H, et al. Among authors: yang d, yang l, yang h. Nature. 2018 Jan 3;553(7686):106-110. doi: 10.1038/nature25153. Nature. 2018. PMID: 29300013
Full-length human GLP-1 receptor structure without orthosteric ligands.
Wu F, Yang L, Hang K, Laursen M, Wu L, Han GW, Ren Q, Roed NK, Lin G, Hanson MA, Jiang H, Wang MW, Reedtz-Runge S, Song G, Stevens RC. Wu F, et al. Among authors: yang l. Nat Commun. 2020 Mar 9;11(1):1272. doi: 10.1038/s41467-020-14934-5. Nat Commun. 2020. PMID: 32152292 Free PMC article.
Structural basis for molecular recognition at serotonin receptors.
Wang C, Jiang Y, Ma J, Wu H, Wacker D, Katritch V, Han GW, Liu W, Huang XP, Vardy E, McCorvy JD, Gao X, Zhou XE, Melcher K, Zhang C, Bai F, Yang H, Yang L, Jiang H, Roth BL, Cherezov V, Stevens RC, Xu HE. Wang C, et al. Among authors: yang l, yang h. Science. 2013 May 3;340(6132):610-4. doi: 10.1126/science.1232807. Epub 2013 Mar 21. Science. 2013. PMID: 23519210 Free PMC article.
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site.
Wang J, Yang D, Cheng X, Yang L, Wang Z, Dai A, Cai X, Zhang C, Yuliantie E, Liu Q, Jiang H, Liu H, Wang MW, Yang H. Wang J, et al. Among authors: yang d, yang l, yang h. ACS Chem Biol. 2021 Nov 19;16(11):2444-2452. doi: 10.1021/acschembio.1c00552. Epub 2021 Sep 27. ACS Chem Biol. 2021. PMID: 34570476
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