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78 results

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Page 1
Somatic 9p24.1 alterations in HPV- head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity.
Zhao X, Cohen EEW, William WN Jr, Bianchi JJ, Abraham JP, Magee D, Spetzler DB, Gutkind JS, Alexandrov LB, Cavenee WK, Lippman SM, Davoli T. Zhao X, et al. Among authors: abraham jp. Proc Natl Acad Sci U S A. 2022 Nov 22;119(47):e2213835119. doi: 10.1073/pnas.2213835119. Epub 2022 Nov 17. Proc Natl Acad Sci U S A. 2022. PMID: 36395141 Free PMC article.
Clinical Validation of a Machine-learning-derived Signature Predictive of Outcomes from First-line Oxaliplatin-based Chemotherapy in Advanced Colorectal Cancer.
Abraham JP, Magee D, Cremolini C, Antoniotti C, Halbert DD, Xiu J, Stafford P, Berry DA, Oberley MJ, Shields AF, Marshall JL, Salem ME, Falcone A, Grothey A, Hall MJ, Venook AP, Lenz HJ, Helmstetter A, Korn WM, Spetzler DB. Abraham JP, et al. Clin Cancer Res. 2021 Feb 15;27(4):1174-1183. doi: 10.1158/1078-0432.CCR-20-3286. Epub 2020 Dec 8. Clin Cancer Res. 2021. PMID: 33293373
Immune evasion in HPV- head and neck precancer-cancer transition is driven by an aneuploid switch involving chromosome 9p loss.
William WN Jr, Zhao X, Bianchi JJ, Lin HY, Cheng P, Lee JJ, Carter H, Alexandrov LB, Abraham JP, Spetzler DB, Dubinett SM, Cleveland DW, Cavenee W, Davoli T, Lippman SM. William WN Jr, et al. Among authors: abraham jp. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2022655118. doi: 10.1073/pnas.2022655118. Proc Natl Acad Sci U S A. 2021. PMID: 33952700 Free PMC article.
Tumour mutational burden, microsatellite instability, and actionable alterations in metastatic colorectal cancer: Next-generation sequencing results of TRIBE2 study.
Antoniotti C, Korn WM, Marmorino F, Rossini D, Lonardi S, Masi G, Randon G, Conca V, Boccaccino A, Tomasello G, Passardi A, Swensen J, Ugolini C, Oberley M, Tamburini E, Casagrande M, Domenyuk V, Fontanini G, Giordano M, Abraham J, Spetzler D, Falcone A, Lenz HJ, Cremolini C. Antoniotti C, et al. Eur J Cancer. 2021 Sep;155:73-84. doi: 10.1016/j.ejca.2021.06.037. Epub 2021 Aug 5. Eur J Cancer. 2021. PMID: 34365081
Homologous Recombination Deficiency Alterations in Colorectal Cancer: Clinical, Molecular, and Prognostic Implications.
Moretto R, Elliott A, Zhang J, Arai H, Germani MM, Conca V, Xiu J, Stafford P, Oberley M, Abraham J, Spetzler D, Rossini D, Antoniotti C, Marshall J, Shields A, Lopes G, Lonardi S, Pietrantonio F, Tomasello G, Passardi A, Tamburini E, Santini D, Aprile G, Masi G, Falcone A, Lenz HJ, Korn M, Cremolini C. Moretto R, et al. J Natl Cancer Inst. 2022 Feb 7;114(2):271-279. doi: 10.1093/jnci/djab169. J Natl Cancer Inst. 2022. PMID: 34469533 Free PMC article.
Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer.
Arai H, Elliott A, Millstein J, Xiu J, Ou FS, Innocenti F, Wang J, Battaglin F, Jayachandran P, Kawanishi N, Soni S, Zhang W, Sohal D, Goldberg RM, Hall MJ, Scott AJ, Khushman M, Hwang JJ, Lou E, Weinberg BA, Lockhart AC, Shields AF, Abraham JP, Magee D, Stafford P, Zhang J, Venook AP, Korn WM, Lenz HJ. Arai H, et al. Among authors: abraham jp. Oncogene. 2022 Jan;41(2):260-267. doi: 10.1038/s41388-021-02074-z. Epub 2021 Nov 2. Oncogene. 2022. PMID: 34728807 Free PMC article.
78 results