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Insulin Signaling Disruption and INF-γ Upregulation Induce Aβ1-42 and Hyperphosphorylated-Tau Proteins Synthesis and Cell Death after Paraquat Treatment of Primary Hippocampal Cells.
Abascal ML, Sanjuan J, Moyano P, Sola E, Flores A, Garcia JM, Garcia J, Frejo MT, Del Pino J. Abascal ML, et al. Among authors: sola e. Chem Res Toxicol. 2022 Dec 19;35(12):2214-2218. doi: 10.1021/acs.chemrestox.2c00278. Epub 2022 Nov 17. Chem Res Toxicol. 2022. PMID: 36394833 Free PMC article.
Manganese increases Aβ and Tau protein levels through proteasome 20S and heat shock proteins 90 and 70 alteration, leading to SN56 cholinergic cell death following single and repeated treatment.
Moyano P, García JM, García J, Anadon MJ, Naval MV, Frejo MT, Sola E, Pelayo A, Pino JD. Moyano P, et al. Among authors: sola e. Ecotoxicol Environ Saf. 2020 Oct 15;203:110975. doi: 10.1016/j.ecoenv.2020.110975. Epub 2020 Jul 14. Ecotoxicol Environ Saf. 2020. PMID: 32678756
Bisphenol A single and repeated treatment increases HDAC2, leading to cholinergic neurotransmission dysfunction and SN56 cholinergic apoptotic cell death through AChE variants overexpression and NGF/TrkA/P75NTR signaling disruption.
Moyano P, Flores A, García J, García JM, Anadon MJ, Frejo MT, Sola E, Pelayo A, Del Pino J. Moyano P, et al. Among authors: sola e. Food Chem Toxicol. 2021 Nov;157:112614. doi: 10.1016/j.fct.2021.112614. Epub 2021 Oct 14. Food Chem Toxicol. 2021. PMID: 34655688
304 results