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The prophylactic and therapeutic efficacy of the broadly active antiviral ribonucleoside N4-Hydroxycytidine (EIDD-1931) in a mouse model of lethal Ebola virus infection.
Bluemling GR, Mao S, Natchus MG, Painter W, Mulangu S, Lockwood M, De La Rosa A, Brasel T, Comer JE, Freiberg AN, Kolykhalov AA, Painter GR. Bluemling GR, et al. Among authors: comer je. Antiviral Res. 2023 Jan;209:105453. doi: 10.1016/j.antiviral.2022.105453. Epub 2022 Nov 13. Antiviral Res. 2023. PMID: 36379378 Free article.
Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection.
Ekins S, Lingerfelt MA, Comer JE, Freiberg AN, Mirsalis JC, O'Loughlin K, Harutyunyan A, McFarlane C, Green CE, Madrid PB. Ekins S, et al. Among authors: comer je. Antimicrob Agents Chemother. 2018 Jan 25;62(2):e01711-17. doi: 10.1128/AAC.01711-17. Print 2018 Feb. Antimicrob Agents Chemother. 2018. PMID: 29133569 Free PMC article.
First vaccine approval under the FDA Animal Rule.
Beasley DWC, Brasel TL, Comer JE. Beasley DWC, et al. Among authors: comer je. NPJ Vaccines. 2016 Aug 25;1:16013. doi: 10.1038/npjvaccines.2016.13. eCollection 2016. NPJ Vaccines. 2016. PMID: 29263855 Free PMC article.
Repurposing Quinacrine against Ebola Virus Infection In Vivo.
Lane TR, Comer JE, Freiberg AN, Madrid PB, Ekins S. Lane TR, et al. Among authors: comer je. Antimicrob Agents Chemother. 2019 Aug 23;63(9):e01142-19. doi: 10.1128/AAC.01142-19. Print 2019 Sep. Antimicrob Agents Chemother. 2019. PMID: 31307979 Free PMC article.
Pyronaridine tetraphosphate efficacy against Ebola virus infection in guinea pig.
Lane TR, Massey C, Comer JE, Freiberg AN, Zhou H, Dyall J, Holbrook MR, Anantpadma M, Davey RA, Madrid PB, Ekins S. Lane TR, et al. Among authors: comer je. Antiviral Res. 2020 Sep;181:104863. doi: 10.1016/j.antiviral.2020.104863. Epub 2020 Jul 16. Antiviral Res. 2020. PMID: 32682926 Free PMC article.
Mucosal Challenge Ferret Models of Ebola Virus Disease.
Brasel T, Comer JE, Massey S, Smith J, Smith J, Hyde M, Kocsis A, Gainey M, Niemuth N, Triplett C, Rudge T Jr. Brasel T, et al. Among authors: comer je. Pathogens. 2021 Mar 4;10(3):292. doi: 10.3390/pathogens10030292. Pathogens. 2021. PMID: 33806375 Free PMC article.
Cell-Type Apoptosis in Lung during SARS-CoV-2 Infection.
Liu Y, Garron TM, Chang Q, Su Z, Zhou C, Qiu Y, Gong EC, Zheng J, Yin YW, Ksiazek T, Brasel T, Jin Y, Boor P, Comer JE, Gong B. Liu Y, et al. Among authors: comer je. Pathogens. 2021 Apr 23;10(5):509. doi: 10.3390/pathogens10050509. Pathogens. 2021. PMID: 33922476 Free PMC article.
The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody.
Chan CEZ, Seah SGK, Chye H, Massey S, Torres M, Lim APC, Wong SKK, Neo JJY, Wong PS, Lim JH, Loh GSL, Wang D, Boyd-Kirkup JD, Guan S, Thakkar D, Teo GH, Purushotorman K, Hutchinson PE, Young BE, Low JG, MacAry PA, Hentze H, Prativadibhayankara VS, Ethirajulu K, Comer JE, Tseng CK, Barrett ADT, Ingram PJ, Brasel T, Hanson BJ. Chan CEZ, et al. Among authors: comer je. PLoS One. 2021 Jun 23;16(6):e0253487. doi: 10.1371/journal.pone.0253487. eCollection 2021. PLoS One. 2021. PMID: 34161386 Free PMC article.
Natural history of disease in cynomolgus monkeys exposed to Ebola virus Kikwit strain demonstrates the reliability of this non-human primate model for Ebola virus disease.
Niemuth NA, Fallacara D, Triplett CA, Tamrakar SM, Rajbhandari A, Florence C, Ward L, Griffiths A, Carrion R Jr, Goez-Gazi Y, Alfson KJ, Staples HM, Brasel T, Comer JE, Massey S, Smith J, Kocsis A, Lowry J, Johnston SC, Nalca A, Goff AJ, Shurtleff AC, Pitt ML, Trefry J, Fay MP. Niemuth NA, et al. Among authors: comer je. PLoS One. 2021 Jul 2;16(7):e0252874. doi: 10.1371/journal.pone.0252874. eCollection 2021. PLoS One. 2021. PMID: 34214118 Free PMC article.
59 results