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VIP152 is a selective CDK9 inhibitor with pre-clinical in vitro and in vivo efficacy in chronic lymphocytic leukemia.
Sher S, Whipp E, Walker J, Zhang P, Beaver L, Williams K, Orwick S, Ravikrishnan J, Walker B, Perry E, Gregory C, Purcell M, Pan A, Yan P, Alinari L, Johnson AJ, Frigault MM, Greer JM, Hamdy A, Izumi R, Mo X, Sampath D, Woyach J, Blachly J, Byrd JC, Lapalombella R. Sher S, et al. Among authors: ravikrishnan j. Leukemia. 2023 Feb;37(2):326-338. doi: 10.1038/s41375-022-01758-z. Epub 2022 Nov 14. Leukemia. 2023. PMID: 36376377 Free PMC article.
HSP90 inhibition depletes DNA repair proteins to sensitize acute myelogenous leukemia to nucleoside analog chemotherapeutics.
Lai TH, Mitchell S, Wu PJ, Orwick S, Liu C, Ravikrishnan J, Woyach J, Mims A, Plunkett W, Puduvalli VK, Byrd JC, Lapalombella R, Sampath D. Lai TH, et al. Among authors: ravikrishnan j. Leuk Lymphoma. 2019 Sep;60(9):2308-2311. doi: 10.1080/10428194.2019.1571197. Epub 2019 Feb 18. Leuk Lymphoma. 2019. PMID: 30773117 Free PMC article. No abstract available.
HDAC1 regulates the chromatin landscape to control transcriptional dependencies in chronic lymphocytic leukemia.
Lai TH, Ozer HG, Gasparini P, Nigita G, Distefano R, Yu L, Ravikrishnan J, Yilmaz S, Gallegos J, Shukla S, Puduvalli V, Woyach J, Lapalombella R, Blachly J, Byrd JC, Sampath D. Lai TH, et al. Among authors: ravikrishnan j. Blood Adv. 2023 Jun 27;7(12):2897-2911. doi: 10.1182/bloodadvances.2022007998. Blood Adv. 2023. PMID: 36287107 Free PMC article.
Leukemoid like reaction in a post CABG patient.
Padmakumar G, Ravikrishnan J, Jayakumar P, Prasad K. Padmakumar G, et al. Among authors: ravikrishnan j. Indian J Anaesth. 2014 May;58(3):315-8. doi: 10.4103/0019-5049.135046. Indian J Anaesth. 2014. PMID: 25024477 Free PMC article.