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Immunization with a tri-antigen syphilis vaccine significantly attenuates chancre development, reduces bacterial load, and inhibits dissemination of Treponema pallidum.
Lukehart SA, Molini B, Gomez A, Godornes C, Hof R, Fernandez MC, Pitner RA, Gray SA, Carter D, Giacani L, Cameron CE. Lukehart SA, et al. Among authors: hof r. Vaccine. 2022 Dec 12;40(52):7676-7692. doi: 10.1016/j.vaccine.2022.11.002. Epub 2022 Nov 12. Vaccine. 2022. PMID: 36376214 Free PMC article.
New proteins for a new perspective on syphilis diagnosis.
Smith BC, Simpson Y, Morshed MG, Cowen LL, Hof R, Wetherell C, Cameron CE. Smith BC, et al. Among authors: hof r. J Clin Microbiol. 2013 Jan;51(1):105-11. doi: 10.1128/JCM.01390-12. Epub 2012 Oct 24. J Clin Microbiol. 2013. PMID: 23100335 Free PMC article.
The multifunctional role of the pallilysin-associated Treponema pallidum protein, Tp0750, in promoting fibrinolysis and extracellular matrix component degradation.
Houston S, Russell S, Hof R, Roberts AK, Cullen P, Irvine K, Smith DS, Borchers CH, Tonkin ML, Boulanger MJ, Cameron CE. Houston S, et al. Among authors: hof r. Mol Microbiol. 2014 Feb;91(3):618-34. doi: 10.1111/mmi.12482. Epub 2014 Jan 7. Mol Microbiol. 2014. PMID: 24303899 Free PMC article.
The Structure of Treponema pallidum Tp0751 (Pallilysin) Reveals a Non-canonical Lipocalin Fold That Mediates Adhesion to Extracellular Matrix Components and Interactions with Host Cells.
Parker ML, Houston S, Pětrošová H, Lithgow KV, Hof R, Wetherell C, Kao WC, Lin YP, Moriarty TJ, Ebady R, Cameron CE, Boulanger MJ. Parker ML, et al. Among authors: hof r. PLoS Pathog. 2016 Sep 28;12(9):e1005919. doi: 10.1371/journal.ppat.1005919. eCollection 2016 Sep. PLoS Pathog. 2016. PMID: 27683203 Free PMC article.
Post-translational modification of LipL32 during Leptospira interrogans infection.
Witchell TD, Eshghi A, Nally JE, Hof R, Boulanger MJ, Wunder EA Jr, Ko AI, Haake DA, Cameron CE. Witchell TD, et al. Among authors: hof r. PLoS Negl Trop Dis. 2014 Oct 30;8(10):e3280. doi: 10.1371/journal.pntd.0003280. eCollection 2014 Oct. PLoS Negl Trop Dis. 2014. PMID: 25356675 Free PMC article.
129 results