Krekels E - Search Results

1

Acute and long-term exercise differently modulate plasma levels of oxylipins, endocannabinoids, and their analogues in young sedentary adults: A sub-study and secondary analyses from the ACTIBATE randomized controlled-trial.

Jurado-Fasoli L, Di X, Sanchez-Delgado G, Yang W, Osuna-Prieto FJ, Ortiz-Alvarez L, Krekels E, Harms AC, Hankemeier T, Schönke M, Aguilera CM, Llamas-Elvira JM, Kohler I, Rensen PCN, Ruiz JR, Martinez-Tellez B. Jurado-Fasoli L, et al. Among authors: krekels e. EBioMedicine. 2022 Nov;85:104313. doi: 10.1016/j.ebiom.2022.104313. Epub 2022 Oct 27. EBioMedicine. 2022. PMID: 36374769 Free PMC article. Clinical Trial.

2

Amikacin Pharmacokinetics To Optimize Dosing in Neonates with Perinatal Asphyxia Treated with Hypothermia.

Cristea S, Smits A, Kulo A, Knibbe CAJ, van Weissenbruch M, Krekels EHJ, Allegaert K. Cristea S, et al. Antimicrob Agents Chemother. 2017 Nov 22;61(12):e01282-17. doi: 10.1128/AAC.01282-17. Print 2017 Dec. Antimicrob Agents Chemother. 2017. PMID: 28993332 Free PMC article.

3

Predictive Performance of a Recently Developed Population Pharmacokinetic Model for Morphine and its Metabolites in New Datasets of (Preterm) Neonates, Infants and Children.

Krekels EH, DeJongh J, van Lingen RA, van der Marel CD, Choonara I, Lynn AM, Danhof M, Tibboel D, Knibbe C. Krekels EH, et al. Clin Pharmacokinet. 2011 Jan;50(1):51-63. doi: 10.2165/11536750-000000000-00000. Clin Pharmacokinet. 2011. PMID: 27975238

4

From pediatric covariate model to semiphysiological function for maturation: part I-extrapolation of a covariate model from morphine to Zidovudine.

Krekels EH, Neely M, Panoilia E, Tibboel D, Capparelli E, Danhof M, Mirochnick M, Knibbe CA. Krekels EH, et al. CPT Pharmacometrics Syst Pharmacol. 2012 Oct 3;1(10):e9. doi: 10.1038/psp.2012.11. CPT Pharmacometrics Syst Pharmacol. 2012. PMID: 23887364 Free PMC article.

5

Evidence-based drug treatment for special patient populations through model-based approaches.

Krekels EHJ, van Hasselt JGC, van den Anker JN, Allegaert K, Tibboel D, Knibbe CAJ. Krekels EHJ, et al. Eur J Pharm Sci. 2017 Nov 15;109S:S22-S26. doi: 10.1016/j.ejps.2017.05.022. Epub 2017 May 11. Eur J Pharm Sci. 2017. PMID: 28502674 Free article. Review.

6

Pharmacodynamics and Pharmacokinetics of Morphine After Cardiac Surgery in Children With and Without Down Syndrome.

Valkenburg AJ, Calvier EA, van Dijk M, Krekels EH, O'Hare BP, Casey WF, Mathôt RA, Knibbe CA, Tibboel D, Breatnach CV. Valkenburg AJ, et al. Pediatr Crit Care Med. 2016 Oct;17(10):930-938. doi: 10.1097/PCC.0000000000000904. Pediatr Crit Care Med. 2016. PMID: 27513688

7

Pharmacokinetic considerations for pediatric patients receiving analgesia in the intensive care unit; targeting postoperative, ECMO and hypothermia patients.

Zeilmaker GA, Pokorna P, Mian P, Wildschut ED, Knibbe CAJ, Krekels EHJ, Allegaert K, Tibboel D. Zeilmaker GA, et al. Expert Opin Drug Metab Toxicol. 2018 Apr;14(4):417-428. doi: 10.1080/17425255.2018.1461836. Epub 2018 Apr 11. Expert Opin Drug Metab Toxicol. 2018. PMID: 29623729 Review.

8

Pharmacogenetics and paediatric drug development: issues and consequences to labelling and dosing recommendations.

Krekels EH, van den Anker JN, Baiardi P, Cella M, Cheng KY, Gibb DM, Green H, Iolascon A, Jacqz-Aigrain EM, Knibbe CA, Santen GW, van Schaik RH, Tibboel D, Della Pasqua OE. Krekels EH, et al. Expert Opin Pharmacother. 2007 Aug;8(12):1787-99. doi: 10.1517/14656566.8.12.1787. Expert Opin Pharmacother. 2007. PMID: 17696784 Review.

9

Pharmacokinetic-pharmacodynamic modeling of the inhibitory effects of naproxen on the time-courses of inflammatory pain, fever, and the ex vivo synthesis of TXB2 and PGE2 in rats.

Krekels EH, Angesjö M, Sjögren I, Möller KA, Berge OG, Visser SA. Krekels EH, et al. Pharm Res. 2011 Jul;28(7):1561-76. doi: 10.1007/s11095-011-0389-6. Epub 2011 Feb 23. Pharm Res. 2011. PMID: 21347567

10

Population Pharmacokinetics of Edoxaban in Patients with Non-Valvular Atrial Fibrillation in the ENGAGE AF-TIMI 48 Study, a Phase III Clinical Trial.

Krekels EH, Niebecker R, Karlsson MO, Miller R, Shimizu T, Karlsson KE, Ruff CT, Simonsson US, Jönsson S. Krekels EH, et al. Clin Pharmacokinet. 2016 Sep;55(9):1079-90. doi: 10.1007/s40262-016-0378-3. Clin Pharmacokinet. 2016. PMID: 26951208 Clinical Trial.

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