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Gene targeting as a therapeutic avenue in diseases mediated by the complement alternative pathway.
Immunol Rev. 2023 Jan;313(1):402-419. doi: 10.1111/imr.13149. Epub 2022 Nov 12.
Immunol Rev. 2023.
PMID: 36369963
Free PMC article.
Review.
Functional expression of complement factor I following AAV-mediated gene delivery in the retina of mice and human cells.
Dreismann AK, McClements ME, Barnard AR, Orhan E, Hughes JP, Lachmann PJ, MacLaren RE.
Dreismann AK, et al.
Gene Ther. 2021 May;28(5):265-276. doi: 10.1038/s41434-021-00239-9. Epub 2021 Mar 10.
Gene Ther. 2021.
PMID: 33750925
Free PMC article.
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Adeno-Associated Virus Vector Gene Delivery Elevates Factor I Levels and Downregulates the Complement Alternative Pathway In Vivo.
Ahmad A, Mandwie M, Dreismann AK, Smyth CM, Doyle H, Malik TH, Pickering MC, Lachmann PJ, Alexander IE, Logan GJ.
Ahmad A, et al. Among authors: dreismann ak.
Hum Gene Ther. 2021 Nov;32(21-22):1370-1381. doi: 10.1089/hum.2021.022. Epub 2021 Aug 27.
Hum Gene Ther. 2021.
PMID: 34238030
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