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Epigenetic silencing of GCH1promotes hepatocellular carcinoma growth by activating superoxide anion-mediated ASK1/p38 signaling via inhibiting tetrahydrobiopterin de novo biosynthesis.
Zhong GC, Zhao ZB, Cheng Y, Wang YB, Qiu C, Mao LH, Hu JJ, Cai D, Liu Y, Gong JP, Li SW. Zhong GC, et al. Among authors: mao lh. Free Radic Biol Med. 2021 May 20;168:81-94. doi: 10.1016/j.freeradbiomed.2021.03.025. Epub 2021 Mar 26. Free Radic Biol Med. 2021. PMID: 33781891
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