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pTINCR microprotein promotes epithelial differentiation and suppresses tumor growth through CDC42 SUMOylation and activation.
Boix O, Martinez M, Vidal S, Giménez-Alejandre M, Palenzuela L, Lorenzo-Sanz L, Quevedo L, Moscoso O, Ruiz-Orera J, Ximénez-Embún P, Ciriaco N, Nuciforo P, Stephan-Otto Attolini C, Albà MM, Muñoz J, Tian TV, Varela I, Vivancos A, Ramón Y Cajal S, Muñoz P, Rivas C, Abad M. Boix O, et al. Among authors: abad m. Nat Commun. 2022 Nov 11;13(1):6840. doi: 10.1038/s41467-022-34529-6. Nat Commun. 2022. PMID: 36369429 Free PMC article.
Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins.
Vilas JM, Ferreirós A, Carneiro C, Morey L, Da Silva-Álvarez S, Fernandes T, Abad M, Di Croce L, García-Caballero T, Serrano M, Rivas C, Vidal A, Collado M. Vilas JM, et al. Among authors: abad m. Oncotarget. 2015 Feb 20;6(5):2992-3002. doi: 10.18632/oncotarget.2996. Oncotarget. 2015. PMID: 25576924 Free PMC article.
TUNAR lncRNA Encodes a Microprotein that Regulates Neural Differentiation and Neurite Formation by Modulating Calcium Dynamics.
Senís E, Esgleas M, Najas S, Jiménez-Sábado V, Bertani C, Giménez-Alejandre M, Escriche A, Ruiz-Orera J, Hergueta-Redondo M, Jiménez M, Giralt A, Nuciforo P, Albà MM, Peinado H, Del Toro D, Hove-Madsen L, Götz M, Abad M. Senís E, et al. Among authors: abad m. Front Cell Dev Biol. 2021 Dec 31;9:747667. doi: 10.3389/fcell.2021.747667. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 35036403 Free PMC article.
Cellular Senescence Is Immunogenic and Promotes Antitumor Immunity.
Marin I, Boix O, Garcia-Garijo A, Sirois I, Caballe A, Zarzuela E, Ruano I, Attolini CS, Prats N, López-Domínguez JA, Kovatcheva M, Garralda E, Muñoz J, Caron E, Abad M, Gros A, Pietrocola F, Serrano M. Marin I, et al. Among authors: abad m. Cancer Discov. 2023 Feb 6;13(2):410-431. doi: 10.1158/2159-8290.CD-22-0523. Cancer Discov. 2023. PMID: 36302218 Free PMC article.
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2.
Chaib S, López-Domínguez JA, Lalinde-Gutiérrez M, Prats N, Marin I, Boix O, García-Garijo A, Meyer K, Muñoz MI, Aguilera M, Mateo L, Stephan-Otto Attolini C, Llanos S, Pérez-Ramos S, Escorihuela M, Al-Shahrour F, Cash TP, Tchkonia T, Kirkland JL, Abad M, Gros A, Arribas J, Serrano M. Chaib S, et al. Among authors: abad m. Nat Cancer. 2024 Mar;5(3):448-462. doi: 10.1038/s43018-023-00712-x. Epub 2024 Jan 24. Nat Cancer. 2024. PMID: 38267628 Free PMC article.
AAVvector-mediated in vivo reprogramming into pluripotency.
Senís E, Mosteiro L, Wilkening S, Wiedtke E, Nowrouzi A, Afzal S, Fronza R, Landerer H, Abad M, Niopek D, Schmidt M, Serrano M, Grimm D. Senís E, et al. Among authors: abad m. Nat Commun. 2018 Jul 9;9(1):2651. doi: 10.1038/s41467-018-05059-x. Nat Commun. 2018. PMID: 29985406 Free PMC article.
Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming.
Chondronasiou D, Gill D, Mosteiro L, Urdinguio RG, Berenguer-Llergo A, Aguilera M, Durand S, Aprahamian F, Nirmalathasan N, Abad M, Martin-Herranz DE, Stephan-Otto Attolini C, Prats N, Kroemer G, Fraga MF, Reik W, Serrano M. Chondronasiou D, et al. Among authors: abad m. Aging Cell. 2022 Mar;21(3):e13578. doi: 10.1111/acel.13578. Epub 2022 Mar 2. Aging Cell. 2022. PMID: 35235716 Free PMC article.
The microproteome of cancer: From invisibility to relevance.
Merino-Valverde I, Greco E, Abad M. Merino-Valverde I, et al. Among authors: abad m. Exp Cell Res. 2020 Jul 1;392(1):111997. doi: 10.1016/j.yexcr.2020.111997. Epub 2020 Apr 14. Exp Cell Res. 2020. PMID: 32302626 Free article. Review.
474 results