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Ewing Sarcoma Meets Epigenetics, Immunology and Nanomedicine: Moving Forward into Novel Therapeutic Strategies.
Sánchez-Molina S, Figuerola-Bou E, Sánchez-Margalet V, de la Cruz-Merino L, Mora J, de Álava Casado E, García-Domínguez DJ, Hontecillas-Prieto L. Sánchez-Molina S, et al. Among authors: hontecillas prieto l. Cancers (Basel). 2022 Nov 7;14(21):5473. doi: 10.3390/cancers14215473. Cancers (Basel). 2022. PMID: 36358891 Free PMC article. Review.
A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development.
Castillo-Lluva S, Hontecillas-Prieto L, Blanco-Gómez A, Del Mar Sáez-Freire M, García-Cenador B, García-Criado J, Pérez-Andrés M, Orfao A, Cañamero M, Mao JH, Gridley T, Castellanos-Martín A, Pérez-Losada J. Castillo-Lluva S, et al. Oncogene. 2015 Sep 3;34(36):4777-90. doi: 10.1038/onc.2015.224. Epub 2015 Jun 22. Oncogene. 2015. PMID: 26096931 Free PMC article.
The biological age linked to oxidative stress modifies breast cancer aggressiveness.
Sáez-Freire MDM, Blanco-Gómez A, Castillo-Lluva S, Gómez-Vecino A, Galvis-Jiménez JM, Martín-Seisdedos C, Isidoro-García M, Hontecillas-Prieto L, García-Cenador MB, García-Criado FJ, Patino-Alonso MC, Galindo-Villardón P, Mao JH, Prieto C, Castellanos-Martín A, Kaderali L, Pérez-Losada J. Sáez-Freire MDM, et al. Free Radic Biol Med. 2018 May 20;120:133-146. doi: 10.1016/j.freeradbiomed.2018.03.012. Epub 2018 Mar 14. Free Radic Biol Med. 2018. PMID: 29550329 Free article.
RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein.
Hernandez-Muñoz I, Figuerola E, Sanchez-Molina S, Rodriguez E, Fernández-Mariño AI, Pardo-Pastor C, Bahamonde MI, Fernández-Fernández JM, García-Domínguez DJ, Hontecillas-Prieto L, Lavarino C, Carcaboso AM, de Torres C, Tirado OM, de Alava E, Mora J. Hernandez-Muñoz I, et al. Oncotarget. 2016 Jul 19;7(29):46283-46300. doi: 10.18632/oncotarget.10092. Oncotarget. 2016. PMID: 27317769 Free PMC article.
DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1.
Huertas-Martínez J, Court F, Rello-Varona S, Herrero-Martín D, Almacellas-Rabaiget O, Sáinz-Jaspeado M, Garcia-Monclús S, Lagares-Tena L, Buj R, Hontecillas-Prieto L, Sastre A, Azorin D, Sanjuan X, López-Alemany R, Moran S, Roma J, Gallego S, Mora J, García Del Muro X, Giangrande PH, Peinado MA, Alonso J, de Alava E, Monk D, Esteller M, Tirado OM. Huertas-Martínez J, et al. Cancer Lett. 2017 Feb 1;386:196-207. doi: 10.1016/j.canlet.2016.11.020. Epub 2016 Nov 25. Cancer Lett. 2017. PMID: 27894957
EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma.
Garcia-Monclús S, López-Alemany R, Almacellas-Rabaiget O, Herrero-Martín D, Huertas-Martinez J, Lagares-Tena L, Alba-Pavón P, Hontecillas-Prieto L, Mora J, de Álava E, Rello-Varona S, Giangrande PH, Tirado OM. Garcia-Monclús S, et al. Int J Cancer. 2018 Sep 1;143(5):1188-1201. doi: 10.1002/ijc.31405. Epub 2018 Apr 16. Int J Cancer. 2018. PMID: 29582409 Free PMC article.
32 results