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Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute Leukemia.
Reßing N, Schliehe-Diecks J, Watson PR, Sönnichsen M, Cragin AD, Schöler A, Yang J, Schäker-Hübner L, Borkhardt A, Christianson DW, Bhatia S, Hansen FK. Reßing N, et al. Among authors: sonnichsen m. J Med Chem. 2022 Nov 24;65(22):15457-15472. doi: 10.1021/acs.jmedchem.2c01418. Epub 2022 Nov 9. J Med Chem. 2022. PMID: 36351184 Free PMC article.
Hydroxamic Acids Immobilized on Resins (HAIRs): Synthesis of Dual-Targeting HDAC Inhibitors and HDAC Degraders (PROTACs).
Sinatra L, Bandolik JJ, Roatsch M, Sönnichsen M, Schoeder CT, Hamacher A, Schöler A, Borkhardt A, Meiler J, Bhatia S, Kassack MU, Hansen FK. Sinatra L, et al. Among authors: sonnichsen m. Angew Chem Int Ed Engl. 2020 Dec 7;59(50):22494-22499. doi: 10.1002/anie.202006725. Epub 2020 Oct 9. Angew Chem Int Ed Engl. 2020. PMID: 32780485 Free PMC article.
Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups.
Reßing N, Sönnichsen M, Osko JD, Schöler A, Schliehe-Diecks J, Skerhut A, Borkhardt A, Hauer J, Kassack MU, Christianson DW, Bhatia S, Hansen FK. Reßing N, et al. Among authors: sonnichsen m. J Med Chem. 2020 Sep 24;63(18):10339-10351. doi: 10.1021/acs.jmedchem.9b01888. Epub 2020 Sep 1. J Med Chem. 2020. PMID: 32803970 Free PMC article.
Solid-Phase Synthesis of Cereblon-Recruiting Selective Histone Deacetylase 6 Degraders (HDAC6 PROTACs) with Antileukemic Activity.
Sinatra L, Yang J, Schliehe-Diecks J, Dienstbier N, Vogt M, Gebing P, Bachmann LM, Sönnichsen M, Lenz T, Stühler K, Schöler A, Borkhardt A, Bhatia S, Hansen FK. Sinatra L, et al. Among authors: sonnichsen m. J Med Chem. 2022 Dec 22;65(24):16860-16878. doi: 10.1021/acs.jmedchem.2c01659. Epub 2022 Dec 6. J Med Chem. 2022. PMID: 36473103
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
Multi-tissue RNA-seq and transcriptome characterisation of the spiny dogfish shark (Squalus acanthias) provides a molecular tool for biological research and reveals new genes involved in osmoregulation.
Chana-Munoz A, Jendroszek A, Sønnichsen M, Kristiansen R, Jensen JK, Andreasen PA, Bendixen C, Panitz F. Chana-Munoz A, et al. Among authors: sonnichsen m. PLoS One. 2017 Aug 23;12(8):e0182756. doi: 10.1371/journal.pone.0182756. eCollection 2017. PLoS One. 2017. PMID: 28832628 Free PMC article.
12 results