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RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation.
Mol Cell. 2022 Nov 17;82(22):4262-4276.e5. doi: 10.1016/j.molcel.2022.10.016. Epub 2022 Nov 7.
Mol Cell. 2022.
PMID: 36347258
Free PMC article.
Distinct Binding Preferences between Ras and Raf Family Members and the Impact on Oncogenic Ras Signaling.
Terrell EM, Durrant DE, Ritt DA, Sealover NE, Sheffels E, Spencer-Smith R, Esposito D, Zhou Y, Hancock JF, Kortum RL, Morrison DK.
Terrell EM, et al.
Mol Cell. 2019 Dec 19;76(6):872-884.e5. doi: 10.1016/j.molcel.2019.09.004. Epub 2019 Oct 9.
Mol Cell. 2019.
PMID: 31606273
Free PMC article.
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Ras-Mediated Activation of the Raf Family Kinases.
Terrell EM, Morrison DK.
Terrell EM, et al.
Cold Spring Harb Perspect Med. 2019 Jan 2;9(1):a033746. doi: 10.1101/cshperspect.a033746.
Cold Spring Harb Perspect Med. 2019.
PMID: 29358316
Free PMC article.
Review.
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M-Ras/Shoc2 signaling modulates E-cadherin turnover and cell-cell adhesion during collective cell migration.
Kota P, Terrell EM, Ritt DA, Insinna C, Westlake CJ, Morrison DK.
Kota P, et al. Among authors: terrell em.
Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3536-3545. doi: 10.1073/pnas.1805919116. Epub 2019 Feb 11.
Proc Natl Acad Sci U S A. 2019.
PMID: 30808747
Free PMC article.
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Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.
Murphy BM, Terrell EM, Chirasani VR, Weiss TJ, Lew RE, Holderbaum AM, Dhakal A, Posada V, Fort M, Bodnar MS, Carey LM, Chen M, Burd CJ, Coppola V, Morrison DK, Campbell SL, Burd CE.
Murphy BM, et al. Among authors: terrell em.
Nat Commun. 2022 Jun 7;13(1):3153. doi: 10.1038/s41467-022-30881-9.
Nat Commun. 2022.
PMID: 35672316
Free PMC article.
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Regulation of GTPase function by autophosphorylation.
Johnson CW, Seo HS, Terrell EM, Yang MH, KleinJan F, Gebregiworgis T, Gasmi-Seabrook GMC, Geffken EA, Lakhani J, Song K, Bashyal P, Popow O, Paulo JA, Liu A, Mattos C, Marshall CB, Ikura M, Morrison DK, Dhe-Paganon S, Haigis KM.
Johnson CW, et al. Among authors: terrell em.
Mol Cell. 2022 Mar 3;82(5):950-968.e14. doi: 10.1016/j.molcel.2022.02.011. Epub 2022 Feb 23.
Mol Cell. 2022.
PMID: 35202574
Free PMC article.
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