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Design, synthesis and biological evaluation of hybrid bioisoster derivatives of N-acylhydrazone and furoxan groups with potential and selective anti-Trypanosoma cruzi activity.
Massarico Serafim RA, Gonçalves JE, de Souza FP, de Melo Loureiro AP, Storpirtis S, Krogh R, Andricopulo AD, Dias LC, Ferreira EI. Massarico Serafim RA, et al. Among authors: dias lc. Eur J Med Chem. 2014 Jul 23;82:418-25. doi: 10.1016/j.ejmech.2014.05.077. Epub 2014 Jun 3. Eur J Med Chem. 2014. PMID: 24929292
Novel inhibitors of Plasmodium falciparum based on 2,5-disubstituted furans.
Krake SH, Martinez PDG, McLaren J, Ryan E, Chen G, White K, Charman SA, Campbell S, Willis P, Dias LC. Krake SH, et al. Among authors: dias lc. Eur J Med Chem. 2017 Jan 27;126:929-936. doi: 10.1016/j.ejmech.2016.12.024. Epub 2016 Dec 11. Eur J Med Chem. 2017. PMID: 28002775
2,3,8-Trisubstituted Quinolines with Antimalarial Activity.
Martinez PDG, Krake SH, Poggi ML, Campbell SF, Willis PA, Dias LC. Martinez PDG, et al. Among authors: dias lc. An Acad Bras Cienc. 2018 May 21;90(1 Suppl 2):1215-1231. doi: 10.1590/0001-3765201820170820. Print 2018. An Acad Bras Cienc. 2018. PMID: 29791525 Free article.
Benzimidazole inhibitors of the major cysteine protease of Trypanosoma brucei.
Pereira GA, Santos LH, Wang SC, Martins LC, Villela FS, Liao W, Dessoy MA, Dias LC, Andricopulo AD, Costa MA, Nagem RA, Caffrey CR, Liedl KR, Caffarena ER, Ferreira RS. Pereira GA, et al. Among authors: dias lc. Future Med Chem. 2019 Jul;11(13):1537-1551. doi: 10.4155/fmc-2018-0523. Future Med Chem. 2019. PMID: 31469332 Free PMC article.
Discovery of Potent, Reversible, and Competitive Cruzain Inhibitors with Trypanocidal Activity: A Structure-Based Drug Design Approach.
de Souza ML, de Oliveira Rezende Junior C, Ferreira RS, Espinoza Chávez RM, Ferreira LLG, Slafer BW, Magalhães LG, Krogh R, Oliva G, Cruz FC, Dias LC, Andricopulo AD. de Souza ML, et al. Among authors: dias lc. J Chem Inf Model. 2020 Feb 24;60(2):1028-1041. doi: 10.1021/acs.jcim.9b00802. Epub 2019 Dec 11. J Chem Inf Model. 2020. PMID: 31765144
Structure-Based and Molecular Modeling Studies for the Discovery of Cyclic Imides as Reversible Cruzain Inhibitors With Potent Anti-Trypanosoma cruzi Activity.
Ferreira RAA, Pauli I, Sampaio TS, de Souza ML, Ferreira LLG, Magalhães LG, Rezende CO Jr, Ferreira RS, Krogh R, Dias LC, Andricopulo AD. Ferreira RAA, et al. Among authors: dias lc. Front Chem. 2019 Nov 25;7:798. doi: 10.3389/fchem.2019.00798. eCollection 2019. Front Chem. 2019. PMID: 31824926 Free PMC article.
150 results