de Witte PAM - Search Results

1

Modulation of sleep behavior in zebrafish larvae by pharmacological targeting of the orexin receptor.

Pardon M, Claes P, Druwé S, Martini M, Siekierska A, Menet C, de Witte PAM, Copmans D. Pardon M, et al. Among authors: de witte pam. Front Pharmacol. 2022 Oct 10;13:1012622. doi: 10.3389/fphar.2022.1012622. eCollection 2022. Front Pharmacol. 2022. PMID: 36339591 Free PMC article.

2

Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes.

Schubert J, Siekierska A, Langlois M, May P, Huneau C, Becker F, Muhle H, Suls A, Lemke JR, de Kovel CG, Thiele H, Konrad K, Kawalia A, Toliat MR, Sander T, Rüschendorf F, Caliebe A, Nagel I, Kohl B, Kecskés A, Jacmin M, Hardies K, Weckhuysen S, Riesch E, Dorn T, Brilstra EH, Baulac S, Møller RS, Hjalgrim H, Koeleman BP; EuroEPINOMICS RES Consortium; Jurkat-Rott K, Lehman-Horn F, Roach JC, Glusman G, Hood L, Galas DJ, Martin B, de Witte PA, Biskup S, De Jonghe P, Helbig I, Balling R, Nürnberg P, Crawford AD, Esguerra CV, Weber YG, Lerche H. Schubert J, et al. Nat Genet. 2014 Dec;46(12):1327-32. doi: 10.1038/ng.3130. Epub 2014 Nov 2. Nat Genet. 2014. PMID: 25362483

3

Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine.

Zhang Y, Kecskés A, Copmans D, Langlois M, Crawford AD, Ceulemans B, Lagae L, de Witte PA, Esguerra CV. Zhang Y, et al. PLoS One. 2015 May 12;10(5):e0125898. doi: 10.1371/journal.pone.0125898. eCollection 2015. PLoS One. 2015. PMID: 25965391 Free PMC article.

4

A KNIME-Based Analysis of the Zebrafish Photomotor Response Clusters the Phenotypes of 14 Classes of Neuroactive Molecules.

Copmans D, Meinl T, Dietz C, van Leeuwen M, Ortmann J, Berthold MR, de Witte PA. Copmans D, et al. J Biomol Screen. 2016 Jun;21(5):427-36. doi: 10.1177/1087057115618348. Epub 2015 Dec 4. J Biomol Screen. 2016. PMID: 26637551

5

Gain-of-function FHF1 mutation causes early-onset epileptic encephalopathy with cerebellar atrophy.

Siekierska A, Isrie M, Liu Y, Scheldeman C, Vanthillo N, Lagae L, de Witte PA, Van Esch H, Goldfarb M, Buyse GM. Siekierska A, et al. Neurology. 2016 Jun 7;86(23):2162-70. doi: 10.1212/WNL.0000000000002752. Epub 2016 May 4. Neurology. 2016. PMID: 27164707 Free PMC article.

6

Use of Zebrafish Larvae as a Multi-Endpoint Platform to Characterize the Toxicity Profile of Silica Nanoparticles.

Pham DH, De Roo B, Nguyen XB, Vervaele M, Kecskés A, Ny A, Copmans D, Vriens H, Locquet JP, Hoet P, de Witte PA. Pham DH, et al. Sci Rep. 2016 Nov 22;6:37145. doi: 10.1038/srep37145. Sci Rep. 2016. PMID: 27872490 Free PMC article.

7

Pharmacological Analysis of the Anti-epileptic Mechanisms of Fenfluramine in scn1a Mutant Zebrafish.

Sourbron J, Smolders I, de Witte P, Lagae L. Sourbron J, et al. Front Pharmacol. 2017 Apr 6;8:191. doi: 10.3389/fphar.2017.00191. eCollection 2017. Front Pharmacol. 2017. PMID: 28428755 Free PMC article.

8

Automated analysis of brain activity for seizure detection in zebrafish models of epilepsy.

Hunyadi B, Siekierska A, Sourbron J, Copmans D, de Witte PAM. Hunyadi B, et al. Among authors: de witte pam. J Neurosci Methods. 2017 Aug 1;287:13-24. doi: 10.1016/j.jneumeth.2017.05.024. Epub 2017 Jun 1. J Neurosci Methods. 2017. PMID: 28577986

9

Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish.

Zhang Y, Vanmeert M, Siekierska A, Ny A, John J, Callewaert G, Lescrinier E, Dehaen W, de Witte PAM, Kaminski RM. Zhang Y, et al. Among authors: de witte pam. Sci Rep. 2017 Aug 3;7(1):7195. doi: 10.1038/s41598-017-06294-w. Sci Rep. 2017. PMID: 28775328 Free PMC article.

10

Scheldeman C, Mills JD, Siekierska A, Serra I, Copmans D, Iyer AM, Whalley BJ, Maes J, Jansen AC, Lagae L, Aronica E, de Witte PAM. Scheldeman C, et al. Among authors: de witte pam. Neurobiol Dis. 2017 Dec;108:225-237. doi: 10.1016/j.nbd.2017.09.004. Epub 2017 Sep 6. Neurobiol Dis. 2017. PMID: 28888969

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