Sherer EC - Search Results

1

One-Step Regio- and Stereoselective Electrochemical Synthesis of Orexin Receptor Antagonist Oxidative Metabolites.

Yao H, Sherer EC, Lu M, Small J, Martin GE, Lam YH, Chen Q, Helmy R, Liu Y, Chen H. Yao H, et al. Among authors: sherer ec. J Org Chem. 2022 Nov 18;87(22):15011-15021. doi: 10.1021/acs.joc.2c01311. Epub 2022 Nov 2. J Org Chem. 2022. PMID: 36322780 Free PMC article.

2

Absolute configuration of remisporines A & B.

Sherer EC, Cheeseman JR, Williamson RT. Sherer EC, et al. Org Biomol Chem. 2015 Apr 14;13(14):4169-73. doi: 10.1039/c5ob00082c. Epub 2015 Mar 4. Org Biomol Chem. 2015. PMID: 25735997

3

Homodecoupled 1,1- and 1,n-ADEQUATE: Pivotal NMR Experiments for the Structure Revision of Cryptospirolepine.

Saurí J, Bermel W, Buevich AV, Sherer EC, Joyce LA, Sharaf MH, Schiff PL Jr, Parella T, Williamson RT, Martin GE. Saurí J, et al. Among authors: sherer ec. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10160-4. doi: 10.1002/anie.201502540. Epub 2015 Jul 15. Angew Chem Int Ed Engl. 2015. PMID: 26178441

4

Capture of reactive monophosphine-ligated palladium(0) intermediates by mass spectrometry.

Zheng Q, Liu Y, Chen Q, Hu M, Helmy R, Sherer EC, Welch CJ, Chen H. Zheng Q, et al. Among authors: sherer ec. J Am Chem Soc. 2015 Nov 11;137(44):14035-8. doi: 10.1021/jacs.5b08905. Epub 2015 Oct 28. J Am Chem Soc. 2015. PMID: 26498505

5

Definitive Metabolite Identification Coupled with Automated Ligand Identification System (ALIS) Technology: A Novel Approach to Uncover Structure-Activity Relationships and Guide Drug Design in a Factor IXa Inhibitor Program.

Zhang T, Liu Y, Yang X, Martin GE, Yao H, Shang J, Bugianesi RM, Ellsworth KP, Sonatore LM, Nizner P, Sherer EC, Hill SE, Knemeyer IW, Geissler WM, Dandliker PJ, Helmy R, Wood HB. Zhang T, et al. Among authors: sherer ec. J Med Chem. 2016 Mar 10;59(5):1818-29. doi: 10.1021/acs.jmedchem.5b01293. Epub 2016 Feb 22. J Med Chem. 2016. PMID: 26871940

6

Mechanistic Study of the Gas-Phase In-Source Hofmann Elimination of Doubly Quaternized Cinchona-Alkaloid Based Phase-Transfer Catalysts by (+)-Electrospray Ionization/Tandem Mass Spectrometry.

Yang RS, Sheng H, Lexa KW, Sherer EC, Zhang LK, Xiang B, Helmy R, Mao B. Yang RS, et al. Among authors: sherer ec. J Am Soc Mass Spectrom. 2017 Mar;28(3):452-460. doi: 10.1007/s13361-016-1583-x. Epub 2017 Jan 18. J Am Soc Mass Spectrom. 2017. PMID: 28101849

7

A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions.

Ji Y, Li H, Hyde AM, Chen Q, Belyk KM, Lexa KW, Yin J, Sherer EC, Williamson RT, Brunskill A, Ren S, Campeau LC, Davies IW, Ruck RT. Ji Y, et al. Among authors: sherer ec. Chem Sci. 2017 Apr 1;8(4):2841-2851. doi: 10.1039/c6sc05472b. Epub 2017 Jan 19. Chem Sci. 2017. PMID: 28553522 Free PMC article.

8

Model for the Enantioselectivity of Asymmetric Intramolecular Alkylations by Bis-Quaternized Cinchona Alkaloid-Derived Catalysts.

He CQ, Simon A, Lam YH, Brunskill APJ, Yasuda N, Tan J, Hyde AM, Sherer EC, Houk KN. He CQ, et al. Among authors: sherer ec. J Org Chem. 2017 Aug 18;82(16):8645-8650. doi: 10.1021/acs.joc.7b01577. Epub 2017 Jul 31. J Org Chem. 2017. PMID: 28731701

9

Selective Formation of Functionalized α-Quaternary Malononitriles toward 5,5-Disubstituted Pyrrolopyrimidinones.

Whitehead A, Zhang Y, McCabe Dunn J, Sherer EC, Lam YH, Stelmach J, Sun A, Shiroda M, Orr RK, Waddell ST, Raghavan S. Whitehead A, et al. Among authors: sherer ec. Org Lett. 2017 Sep 1;19(17):4448-4451. doi: 10.1021/acs.orglett.7b01930. Epub 2017 Aug 16. Org Lett. 2017. PMID: 28812897

10

Computational prediction of chemical reactions: current status and outlook.

Engkvist O, Norrby PO, Selmi N, Lam YH, Peng Z, Sherer EC, Amberg W, Erhard T, Smyth LA. Engkvist O, et al. Among authors: sherer ec. Drug Discov Today. 2018 Jun;23(6):1203-1218. doi: 10.1016/j.drudis.2018.02.014. Epub 2018 Mar 3. Drug Discov Today. 2018. PMID: 29510217 Review.

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