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A specialized metabolic pathway partitions citrate in hydroxyapatite to impact mineralization of bones and teeth.
Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2212178119. doi: 10.1073/pnas.2212178119. Epub 2022 Nov 2.
Proc Natl Acad Sci U S A. 2022.
PMID: 36322718
Free PMC article.
Anticancer Properties of Hexosamine Analogs Designed to Attenuate Metabolic Flux through the Hexosamine Biosynthetic Pathway.
Saeui CT, Shah SR, Fernandez-Gil BI, Zhang C, Agatemor C, Dammen-Brower K, Mathew MP, Buettner M, Gowda P, Khare P, Otamendi-Lopez A, Yang S, Zhang H, Le A, Quinoñes-Hinojosa A, Yarema KJ.
Saeui CT, et al.
ACS Chem Biol. 2023 Jan 20;18(1):151-165. doi: 10.1021/acschembio.2c00784. Epub 2023 Jan 10.
ACS Chem Biol. 2023.
PMID: 36626752
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Airway and Systemic Prostaglandin E2 Association with COPD Symptoms and Macrophage Phenotype.
Tejwani V, Villabona-Rueda AF, Khare P, Zhang C, Le A, Putcha N, D'Alessio F, Alexis NE, Hansel NN, Fawzy A.
Tejwani V, et al.
Chronic Obstr Pulm Dis. 2023 Apr 27;10(2):159-169. doi: 10.15326/jcopdf.2022.0375.
Chronic Obstr Pulm Dis. 2023.
PMID: 36976551
Free PMC article.
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Function and regulation of a steroidogenic CYP450 enzyme in the mitochondrion of Toxoplasma gondii.
Asady B, Sampels V, Romano JD, Levitskaya J, Lige B, Khare P, Le A, Coppens I.
Asady B, et al.
PLoS Pathog. 2023 Aug 31;19(8):e1011566. doi: 10.1371/journal.ppat.1011566. eCollection 2023 Aug.
PLoS Pathog. 2023.
PMID: 37651449
Free PMC article.
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Cancer cells employ lipid droplets to survive toxic stress.
Kostecka LG, Mendez S, Li M, Khare P, Zhang C, Le A, Amend SR, Pienta KJ.
Kostecka LG, et al.
Prostate. 2024 May;84(7):644-655. doi: 10.1002/pros.24680. Epub 2024 Feb 26.
Prostate. 2024.
PMID: 38409853
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Excoriation Disorder Is Characterized by Systemic Glutamatergic Dysfunction.
Bordeaux ZA, Reddy SV, Ma EZ, Cornman H, Pritchard T, Marani M, Lu W, Guo S, Zhang C, Khare P, Le A, Kwatra MM, Kwatra SG.
Bordeaux ZA, et al.
J Invest Dermatol. 2024 Mar 4:S0022-202X(24)00161-1. doi: 10.1016/j.jid.2024.02.005. Online ahead of print.
J Invest Dermatol. 2024.
PMID: 38447865
No abstract available.
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Dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila.
Gabrawy MM, Westbrook R, King A, Khosravian N, Ochaney N, DeCarvalho T, Wang Q, Yu Y, Huang Q, Said A, Abadir M, Zhang C, Khare P, Fairman JE, Le A, Milne GL, Vonhoff FJ, Walston JD, Abadir PM.
Gabrawy MM, et al.
Aging Cell. 2024 Apr;23(4):e14102. doi: 10.1111/acel.14102. Epub 2024 Mar 13.
Aging Cell. 2024.
PMID: 38481042
Free PMC article.
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