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Semaphorin 4D induces articular cartilage destruction and inflammation in joints by transcriptionally reprogramming chondrocytes.
Murakami T, Takahata Y, Hata K, Ebina K, Hirose K, Ruengsinpinya L, Nakaminami Y, Etani Y, Kobayashi S, Maruyama T, Nakano H, Kaneko T, Toyosawa S, Asahara H, Nishimura R. Murakami T, et al. Among authors: nakano h. Sci Signal. 2022 Nov;15(758):eabl5304. doi: 10.1126/scisignal.abl5304. Epub 2022 Nov 1. Sci Signal. 2022. PMID: 36318619
Interleukin-11 links oxidative stress and compensatory proliferation.
Nishina T, Komazawa-Sakon S, Yanaka S, Piao X, Zheng DM, Piao JH, Kojima Y, Yamashina S, Sano E, Putoczki T, Doi T, Ueno T, Ezaki J, Ushio H, Ernst M, Tsumoto K, Okumura K, Nakano H. Nishina T, et al. Among authors: nakano h. Sci Signal. 2012 Jan 17;5(207):ra5. doi: 10.1126/scisignal.2002056. Sci Signal. 2012. PMID: 22253262
Blockade of TNF receptor superfamily 1 (TNFR1)-dependent and TNFR1-independent cell death is crucial for normal epidermal differentiation.
Piao X, Miura R, Miyake S, Komazawa-Sakon S, Koike M, Shindo R, Takeda J, Hasegawa A, Abe R, Nishiyama C, Mikami T, Yagita H, Uchiyama Y, Nakano H. Piao X, et al. Among authors: nakano h. J Allergy Clin Immunol. 2019 Jan;143(1):213-228.e10. doi: 10.1016/j.jaci.2018.02.043. Epub 2018 Mar 27. J Allergy Clin Immunol. 2019. PMID: 29596938
c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.
Piao X, Komazawa-Sakon S, Nishina T, Koike M, Piao JH, Ehlken H, Kurihara H, Hara M, Van Rooijen N, Schütz G, Ohmuraya M, Uchiyama Y, Yagita H, Okumura K, He YW, Nakano H. Piao X, et al. Among authors: nakano h. Sci Signal. 2012 Dec 18;5(255):ra93. doi: 10.1126/scisignal.2003558. Sci Signal. 2012. PMID: 23250397 Free PMC article.
HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.
Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, Tanaka K, Takahashi H, Sawasaki T, Inoue S, Oshiumi H, Seya T, Nakano H, Tanaka Y, Iwai K, Inoue JI. Shibata Y, et al. Among authors: nakano h. PLoS Pathog. 2017 Jan 19;13(1):e1006162. doi: 10.1371/journal.ppat.1006162. eCollection 2017 Jan. PLoS Pathog. 2017. PMID: 28103322 Free PMC article.
The AP-1 transcription factor JunB is required for Th17 cell differentiation.
Yamazaki S, Tanaka Y, Araki H, Kohda A, Sanematsu F, Arasaki T, Duan X, Miura F, Katagiri T, Shindo R, Nakano H, Ito T, Fukui Y, Endo S, Sumimoto H. Yamazaki S, et al. Among authors: nakano h. Sci Rep. 2017 Dec 12;7(1):17402. doi: 10.1038/s41598-017-17597-3. Sci Rep. 2017. PMID: 29234109 Free PMC article.
3,724 results