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Network inference from perturbation time course data.
Sarmah D, Smith GR, Bouhaddou M, Stern AD, Erskine J, Birtwistle MR. Sarmah D, et al. Among authors: birtwistle mr. NPJ Syst Biol Appl. 2022 Nov 1;8(1):42. doi: 10.1038/s41540-022-00253-6. NPJ Syst Biol Appl. 2022. PMID: 36316338 Free PMC article.
CNS Anticancer Drug Discovery and Development Conference White Paper.
Levin VA, Tonge PJ, Gallo JM, Birtwistle MR, Dar AC, Iavarone A, Paddison PJ, Heffron TP, Elmquist WF, Lachowicz JE, Johnson TW, White FM, Sul J, Smith QR, Shen W, Sarkaria JN, Samala R, Wen PY, Berry DA, Petter RC. Levin VA, et al. Among authors: birtwistle mr. Neuro Oncol. 2015 Nov;17 Suppl 6(Suppl 6):vi1-26. doi: 10.1093/neuonc/nov169. Neuro Oncol. 2015. PMID: 26403167 Free PMC article.
Extracellular signal-regulated kinase regulates RhoA activation and tumor cell plasticity by inhibiting guanine exchange factor H1 activity.
von Thun A, Preisinger C, Rath O, Schwarz JP, Ward C, Monsefi N, Rodríguez J, Garcia-Munoz A, Birtwistle M, Bienvenut W, Anderson KI, Kolch W, von Kriegsheim A. von Thun A, et al. Mol Cell Biol. 2013 Nov;33(22):4526-37. doi: 10.1128/MCB.00585-13. Epub 2013 Sep 16. Mol Cell Biol. 2013. PMID: 24043311 Free PMC article.
Raf family kinases: old dogs have learned new tricks.
Matallanas D, Birtwistle M, Romano D, Zebisch A, Rauch J, von Kriegsheim A, Kolch W. Matallanas D, et al. Genes Cancer. 2011 Mar;2(3):232-60. doi: 10.1177/1947601911407323. Genes Cancer. 2011. PMID: 21779496 Free PMC article.
Cell fate decisions are specified by the dynamic ERK interactome.
von Kriegsheim A, Baiocchi D, Birtwistle M, Sumpton D, Bienvenut W, Morrice N, Yamada K, Lamond A, Kalna G, Orton R, Gilbert D, Kolch W. von Kriegsheim A, et al. Nat Cell Biol. 2009 Dec;11(12):1458-64. doi: 10.1038/ncb1994. Epub 2009 Nov 22. Nat Cell Biol. 2009. PMID: 19935650 Free PMC article.
Late gestation under- and overnutrition have differential impacts when combined with a post-natal obesogenic diet on glucose-lactate-insulin adaptations during metabolic challenges in adolescent sheep.
Khanal P, Axel AM, Kongsted AH, Husted SV, Johnsen L, Pandey D, Pedersen KL, Birtwistle M, Markussen B, Kadarmideen HN, Nielsen MO. Khanal P, et al. Acta Physiol (Oxf). 2015 Feb;213(2):519-36. doi: 10.1111/apha.12391. Epub 2014 Oct 13. Acta Physiol (Oxf). 2015. PMID: 25204637
Novel somatic mutations to PI3K pathway genes in metastatic melanoma.
Shull AY, Latham-Schwark A, Ramasamy P, Leskoske K, Oroian D, Birtwistle MR, Buckhaults PJ. Shull AY, et al. Among authors: birtwistle mr. PLoS One. 2012;7(8):e43369. doi: 10.1371/journal.pone.0043369. Epub 2012 Aug 17. PLoS One. 2012. PMID: 22912864 Free PMC article.
Transcriptomes and shRNA suppressors in a TP53 allele-specific model of early-onset colon cancer in African Americans.
Weige CC, Birtwistle MR, Mallick H, Yi N, Berrong Z, Cloessner E, Duff K, Tidwell J, Clendenning M, Wilkerson B, Farrell C, Bunz F, Ji H, Shtutman M, Creek KE, Banister CE, Buckhaults PJ. Weige CC, et al. Among authors: birtwistle mr. Mol Cancer Res. 2014 Jul;12(7):1029-41. doi: 10.1158/1541-7786.MCR-13-0286-T. Epub 2014 Apr 17. Mol Cancer Res. 2014. PMID: 24743655 Free PMC article.
76 results