Czuba LC - Search Results

1

Impact of Pregnancy and Vitamin A Supplementation on CYP2D6 Activity.

Amaeze OU, Czuba LC, Yadav AS, Fay EE, LaFrance J, Shum S, Moreni SL, Mao J, Huang W, Isoherranen N, Hebert MF. Amaeze OU, et al. Among authors: czuba lc. J Clin Pharmacol. 2023 Mar;63(3):363-372. doi: 10.1002/jcph.2169. Epub 2022 Nov 15. J Clin Pharmacol. 2023. PMID: 36309846 Free PMC article. Clinical Trial.

2

Human bile acid transporter ASBT (SLC10A2) forms functional non-covalent homodimers and higher order oligomers.

Chothe PP, Czuba LC, Moore RH, Swaan PW. Chothe PP, et al. Among authors: czuba lc. Biochim Biophys Acta Biomembr. 2018 Mar;1860(3):645-653. doi: 10.1016/j.bbamem.2017.11.016. Epub 2017 Dec 1. Biochim Biophys Acta Biomembr. 2018. PMID: 29198943 Free PMC article.

3

Post-translational modifications of transporters.

Czuba LC, Hillgren KM, Swaan PW. Czuba LC, et al. Pharmacol Ther. 2018 Dec;192:88-99. doi: 10.1016/j.pharmthera.2018.06.013. Epub 2018 Jun 30. Pharmacol Ther. 2018. PMID: 29966598 Free PMC article. Review.

4

The retinoic acid hydroxylase Cyp26a1 has minor effects on postnatal vitamin A homeostasis, but is required for exogenous atRA clearance.

Zhong G, Hogarth C, Snyder JM, Palau L, Topping T, Huang W, Czuba LC, LaFrance J, Ghiaur G, Isoherranen N. Zhong G, et al. Among authors: czuba lc. J Biol Chem. 2019 Jul 19;294(29):11166-11179. doi: 10.1074/jbc.RA119.009023. Epub 2019 Jun 5. J Biol Chem. 2019. PMID: 31167781 Free PMC article.

5

Mechanistic PBPK Modeling of Urine pH Effect on Renal and Systemic Disposition of Methamphetamine and Amphetamine.

Huang W, Czuba LC, Isoherranen N. Huang W, et al. Among authors: czuba lc. J Pharmacol Exp Ther. 2020 Jun;373(3):488-501. doi: 10.1124/jpet.120.264994. Epub 2020 Mar 20. J Pharmacol Exp Ther. 2020. PMID: 32198137 Free PMC article.

6

Analysis of vitamin A and retinoids in biological matrices.

Czuba LC, Zhong G, Yabut KC, Isoherranen N. Czuba LC, et al. Methods Enzymol. 2020;637:309-340. doi: 10.1016/bs.mie.2020.02.010. Epub 2020 Mar 26. Methods Enzymol. 2020. PMID: 32359651 Free PMC article.

7

Knockout of Cyp26a1 and Cyp26b1 during postnatal life causes reduced lifespan, dermatitis, splenomegaly, and systemic inflammation in mice.

Snyder JM, Zhong G, Hogarth C, Huang W, Topping T, LaFrance J, Palau L, Czuba LC, Griswold M, Ghiaur G, Isoherranen N. Snyder JM, et al. Among authors: czuba lc. FASEB J. 2020 Dec;34(12):15788-15804. doi: 10.1096/fj.202001734R. Epub 2020 Oct 26. FASEB J. 2020. PMID: 33105029 Free PMC article.

8

Altered vitamin A metabolism in human liver slices corresponds to fibrogenesis.

Czuba LC, Wu X, Huang W, Hollingshead N, Roberto JB, Kenerson HL, Yeung RS, Crispe IN, Isoherranen N. Czuba LC, et al. Clin Transl Sci. 2021 May;14(3):976-989. doi: 10.1111/cts.12962. Epub 2021 Feb 2. Clin Transl Sci. 2021. PMID: 33382909 Free PMC article.

9

Pregnancy Has No Clinically Significant Effect on the Pharmacokinetics of Bupropion or Its Metabolites.

Fay EE, Czuba LC, Sager JE, Shum S, Stephenson-Famy A, Isoherranen N. Fay EE, et al. Among authors: czuba lc. Ther Drug Monit. 2021 Dec 1;43(6):780-788. doi: 10.1097/FTD.0000000000000885. Ther Drug Monit. 2021. PMID: 33814540 Free PMC article.

10

Objective Identification of Cannabis Use Levels in Clinical Populations Is Critical for Detecting Pharmacological Outcomes.

Huang W, Czuba LC, Manuzak JA, Martin JN, Hunt PW, Klatt NR, Isoherranen N. Huang W, et al. Among authors: czuba lc. Cannabis Cannabinoid Res. 2022 Dec;7(6):852-864. doi: 10.1089/can.2021.0068. Epub 2021 Nov 18. Cannabis Cannabinoid Res. 2022. PMID: 34793254 Free PMC article.

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