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Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins.
DeForest N, Kavitha B, Hu S, Isaac R, Krohn L, Wang M, Du X, De Arruda Saldanha C, Gylys J, Merli E, Abagyan R, Najmi L, Mohan V; Alnylam Human Genetics; AMP-T2D Consortium; Flannick J, Peloso GM, Gordts PLSM, Heinz S, Deaton AM, Khera AV, Olefsky J, Radha V, Majithia AR. DeForest N, et al. Among authors: isaac r. Cell Genom. 2023 May 30;3(7):100339. doi: 10.1016/j.xgen.2023.100339. eCollection 2023 Jul 12. Cell Genom. 2023. PMID: 37492105 Free PMC article.
TM7SF3 controls TEAD1 splicing to prevent MASH-induced liver fibrosis.
Isaac R, Bandyopadhyay G, Rohm TV, Kang S, Wang J, Pokhrel N, Sakane S, Zapata R, Libster AM, Vinik Y, Berhan A, Kisseleva T, Borok Z, Zick Y, Telese F, Webster NJG, Olefsky JM. Isaac R, et al. Cell Metab. 2024 May 7;36(5):1030-1043.e7. doi: 10.1016/j.cmet.2024.04.003. Epub 2024 Apr 25. Cell Metab. 2024. PMID: 38670107
Strategies for primary HPV test-based cervical cancer screening programme in resource-limited settings in India: Results from a quasi-experimental pragmatic implementation trial.
Oommen AM, Isaac R, Paul B, Weller D, Finkel ML, Thomas A, Ram TS, H R P, Cherian AG, Thomas V, Sadan V, Siva R, Rose A, Marcus TA, Jeyapaul S, K SR, Malini T, N S, Jebaraj P, John NO, Ramesh C, Raj C JJ, Kumar S R, B V B, Dorathy P I, Murali V, N P, K K, Ranjani D P. Oommen AM, et al. Among authors: isaac r. PLoS One. 2024 Apr 5;19(4):e0301385. doi: 10.1371/journal.pone.0301385. eCollection 2024. PLoS One. 2024. PMID: 38578742 Free PMC article. Clinical Trial.
Mental health and societal challenges among forced migrants of diverse sexual orientations, gender identities and gender expressions: health professionals' descriptions and interpretations.
Gottvall M, Kissiti R, Ainembabazi R, Bergman H, Eldebo A, Isaac R, Yasin S, Jirwe M, Carlsson T. Gottvall M, et al. Among authors: isaac r. Cult Health Sex. 2024 Jan 22:1-16. doi: 10.1080/13691058.2023.2298479. Online ahead of print. Cult Health Sex. 2024. PMID: 38250794
336 results