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A seven-transmembrane protein-TM7SF3, resides in nuclear speckles and regulates alternative splicing.
iScience. 2022 Oct 4;25(11):105270. doi: 10.1016/j.isci.2022.105270. eCollection 2022 Nov 18.
iScience. 2022.
PMID: 36304109
Free PMC article.
Human Genetics to Identify Therapeutic Targets for NAFLD: Challenges and Opportunities.
Du X, DeForest N, Majithia AR.
Du X, et al. Among authors: deforest n.
Front Endocrinol (Lausanne). 2021 Dec 7;12:777075. doi: 10.3389/fendo.2021.777075. eCollection 2021.
Front Endocrinol (Lausanne). 2021.
PMID: 34950105
Free PMC article.
Review.
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Genetics of Type 2 Diabetes: Implications from Large-Scale Studies.
DeForest N, Majithia AR.
DeForest N, et al.
Curr Diab Rep. 2022 May;22(5):227-235. doi: 10.1007/s11892-022-01462-3. Epub 2022 Mar 19.
Curr Diab Rep. 2022.
PMID: 35305202
Free PMC article.
Review.
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Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism.
Trieger GW, Pessentheiner AR, Purcell SC, Green CR, DeForest N, Willert K, Majithia AR, Metallo CM, Godula K, Gordts PLSM.
Trieger GW, et al. Among authors: deforest n.
J Biol Chem. 2023 May;299(5):104611. doi: 10.1016/j.jbc.2023.104611. Epub 2023 Mar 15.
J Biol Chem. 2023.
PMID: 36931394
Free PMC article.
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Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins.
DeForest N, Kavitha B, Hu S, Isaac R, Krohn L, Wang M, Du X, De Arruda Saldanha C, Gylys J, Merli E, Abagyan R, Najmi L, Mohan V; Alnylam Human Genetics; AMP-T2D Consortium; Flannick J, Peloso GM, Gordts PLSM, Heinz S, Deaton AM, Khera AV, Olefsky J, Radha V, Majithia AR.
DeForest N, et al.
Cell Genom. 2023 May 30;3(7):100339. doi: 10.1016/j.xgen.2023.100339. eCollection 2023 Jul 12.
Cell Genom. 2023.
PMID: 37492105
Free PMC article.
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In Vitro Hepatic Uptake in Human and Monkey Hepatocytes in the Presence and Absence of Serum Protein and Its In Vitro to In Vivo Extrapolation.
Liang X, Park Y, DeForest N, Hao J, Zhao X, Niu C, Wang K, Smith B, Lai Y.
Liang X, et al. Among authors: deforest n.
Drug Metab Dispos. 2020 Dec;48(12):1283-1292. doi: 10.1124/dmd.120.000163. Epub 2020 Oct 9.
Drug Metab Dispos. 2020.
PMID: 33037043
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Cysteine 116 participates in intermolecular bonding of the human VEGF(121) homodimer.
Gaspar NJ, Jue RA, Hu J, Puchacz E, deForest NL, Schellenberger U.
Gaspar NJ, et al. Among authors: deforest nl.
Arch Biochem Biophys. 2002 Aug 1;404(1):126-35. doi: 10.1016/s0003-9861(02)00239-4.
Arch Biochem Biophys. 2002.
PMID: 12127077
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