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A novel valproic acid prodrug as an anticancer agent that enhances doxorubicin anticancer activity and protects normal cells against its toxicity in vitro and in vivo.
Tarasenko N, Cutts SM, Phillips DR, Berkovitch-Luria G, Bardugo-Nissim E, Weitman M, Nudelman A, Rephaeli A. Tarasenko N, et al. Among authors: weitman m. Biochem Pharmacol. 2014 Mar 15;88(2):158-68. doi: 10.1016/j.bcp.2014.01.023. Epub 2014 Jan 24. Biochem Pharmacol. 2014. PMID: 24463168
Synthesis and in vitro evaluation of anti-inflammatory activity of ester and amine derivatives of indoline in RAW 264.7 and peritoneal macrophages.
Furman S, Nissim-Bardugo E, Zeeli S, Weitman M, Nudelman A, Finkin-Groner E, Moradov D, Shifrin H, Schorer-Apelbaum D, Weinstock M. Furman S, et al. Among authors: weitman m. Bioorg Med Chem Lett. 2014 May 15;24(10):2283-7. doi: 10.1016/j.bmcl.2014.03.081. Epub 2014 Apr 2. Bioorg Med Chem Lett. 2014. PMID: 24731278
The Therapeutic Potential of AN-7, a Novel Histone Deacetylase Inhibitor, for Treatment of Mycosis Fungoides/Sezary Syndrome Alone or with Doxorubicin.
Moyal L, Feldbaum N, Goldfeiz N, Rephaeli A, Nudelman A, Weitman M, Tarasenko N, Gorovitz B, Maron L, Yehezkel S, Amitay-Laish I, Lubin I, Hodak E. Moyal L, et al. Among authors: weitman m. PLoS One. 2016 Jan 11;11(1):e0146115. doi: 10.1371/journal.pone.0146115. eCollection 2016. PLoS One. 2016. PMID: 26752418 Free PMC article.
Chemical chaperones targeted to the endoplasmic reticulum (ER) and lysosome prevented neurodegeneration in a C9orf72 repeat expansion drosophila amyotrophic lateral sclerosis (ALS) model.
Azoulay-Ginsburg S, Di Salvio M, Weitman M, Afri M, Ribeiro S, Ebbinghaus S, Cestra G, Gruzman A. Azoulay-Ginsburg S, et al. Among authors: weitman m. Pharmacol Rep. 2021 Apr;73(2):536-550. doi: 10.1007/s43440-021-00226-2. Epub 2021 Mar 4. Pharmacol Rep. 2021. PMID: 33661518
49 results