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HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway.
Krause R, Snyman J, Shi-Hsia H, Muema D, Karim F, Ganga Y, Ngoepe A, Zungu Y, Gazy I, Bernstein M, Khan K, Mazibuko M, Mthabela N, Ramjit D; COMMIT-KZN Team; Limbo O, Jardine J, Sok D, Wilson IA, Hanekom W, Sigal A, Kløverpris H, Ndung'u T, Leslie A. Krause R, et al. Among authors: leslie a. Elife. 2022 Oct 27;11:e79924. doi: 10.7554/eLife.79924. Elife. 2022. PMID: 36300787 Free PMC article.
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.
Kiepiela P, Leslie AJ, Honeyborne I, Ramduth D, Thobakgale C, Chetty S, Rathnavalu P, Moore C, Pfafferott KJ, Hilton L, Zimbwa P, Moore S, Allen T, Brander C, Addo MM, Altfeld M, James I, Mallal S, Bunce M, Barber LD, Szinger J, Day C, Klenerman P, Mullins J, Korber B, Coovadia HM, Walker BD, Goulder PJ. Kiepiela P, et al. Nature. 2004 Dec 9;432(7018):769-75. doi: 10.1038/nature03113. Nature. 2004. PMID: 15592417
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.
Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. Day CL, et al. Among authors: leslie aj. Nature. 2006 Sep 21;443(7109):350-4. doi: 10.1038/nature05115. Epub 2006 Aug 20. Nature. 2006. PMID: 16921384
CD8+ T-cell responses to different HIV proteins have discordant associations with viral load.
Kiepiela P, Ngumbela K, Thobakgale C, Ramduth D, Honeyborne I, Moodley E, Reddy S, de Pierres C, Mncube Z, Mkhwanazi N, Bishop K, van der Stok M, Nair K, Khan N, Crawford H, Payne R, Leslie A, Prado J, Prendergast A, Frater J, McCarthy N, Brander C, Learn GH, Nickle D, Rousseau C, Coovadia H, Mullins JI, Heckerman D, Walker BD, Goulder P. Kiepiela P, et al. Among authors: leslie a. Nat Med. 2007 Jan;13(1):46-53. doi: 10.1038/nm1520. Epub 2006 Dec 17. Nat Med. 2007. PMID: 17173051
Adaptation of HIV-1 to human leukocyte antigen class I.
Kawashima Y, Pfafferott K, Frater J, Matthews P, Payne R, Addo M, Gatanaga H, Fujiwara M, Hachiya A, Koizumi H, Kuse N, Oka S, Duda A, Prendergast A, Crawford H, Leslie A, Brumme Z, Brumme C, Allen T, Brander C, Kaslow R, Tang J, Hunter E, Allen S, Mulenga J, Branch S, Roach T, John M, Mallal S, Ogwu A, Shapiro R, Prado JG, Fidler S, Weber J, Pybus OG, Klenerman P, Ndung'u T, Phillips R, Heckerman D, Harrigan PR, Walker BD, Takiguchi M, Goulder P. Kawashima Y, et al. Among authors: leslie a. Nature. 2009 Apr 2;458(7238):641-5. doi: 10.1038/nature07746. Epub 2009 Feb 25. Nature. 2009. PMID: 19242411 Free PMC article.
Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection.
Thobakgale CF, Prendergast A, Crawford H, Mkhwanazi N, Ramduth D, Reddy S, Molina C, Mncube Z, Leslie A, Prado J, Chonco F, Mphatshwe W, Tudor-Williams G, Jeena P, Blanckenberg N, Dong K, Kiepiela P, Coovadia H, Ndung'u T, Walker BD, Goulder PJ. Thobakgale CF, et al. Among authors: leslie a. J Virol. 2009 Oct;83(19):10234-44. doi: 10.1128/JVI.00921-09. Epub 2009 Jul 15. J Virol. 2009. PMID: 19605475 Free PMC article.
HLA-Cw*03-restricted CD8+ T-cell responses targeting the HIV-1 gag major homology region drive virus immune escape and fitness constraints compensated for by intracodon variation.
Honeyborne I, Codoñer FM, Leslie A, Tudor-Williams G, Luzzi G, Ndung'u T, Walker BD, Goulder PJ, Prado JG. Honeyborne I, et al. Among authors: leslie a. J Virol. 2010 Nov;84(21):11279-88. doi: 10.1128/JVI.01144-10. Epub 2010 Aug 25. J Virol. 2010. PMID: 20739527 Free PMC article.
476 results