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Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics.
Ludwig LS, Lareau CA, Ulirsch JC, Christian E, Muus C, Li LH, Pelka K, Ge W, Oren Y, Brack A, Law T, Rodman C, Chen JH, Boland GM, Hacohen N, Rozenblatt-Rosen O, Aryee MJ, Buenrostro JD, Regev A, Sankaran VG. Ludwig LS, et al. Cell. 2019 Mar 7;176(6):1325-1339.e22. doi: 10.1016/j.cell.2019.01.022. Epub 2019 Feb 28. Cell. 2019. PMID: 30827679 Free PMC article.
Interrogation of human hematopoiesis at single-cell and single-variant resolution.
Ulirsch JC, Lareau CA, Bao EL, Ludwig LS, Guo MH, Benner C, Satpathy AT, Kartha VK, Salem RM, Hirschhorn JN, Finucane HK, Aryee MJ, Buenrostro JD, Sankaran VG. Ulirsch JC, et al. Among authors: ludwig ls. Nat Genet. 2019 Apr;51(4):683-693. doi: 10.1038/s41588-019-0362-6. Epub 2019 Mar 11. Nat Genet. 2019. PMID: 30858613 Free PMC article.
Impaired human hematopoiesis due to a cryptic intronic GATA1 splicing mutation.
Abdulhay NJ, Fiorini C, Verboon JM, Ludwig LS, Ulirsch JC, Zieger B, Lareau CA, Mi X, Roy A, Obeng EA, Erlacher M, Gupta N, Gabriel SB, Ebert BL, Niemeyer CM, Khoriaty RN, Ancliff P, Gazda HT, Wlodarski MW, Sankaran VG. Abdulhay NJ, et al. Among authors: ludwig ls. J Exp Med. 2019 May 6;216(5):1050-1060. doi: 10.1084/jem.20181625. Epub 2019 Mar 26. J Exp Med. 2019. PMID: 30914438 Free PMC article.
Purifying Selection against Pathogenic Mitochondrial DNA in Human T Cells.
Walker MA, Lareau CA, Ludwig LS, Karaa A, Sankaran VG, Regev A, Mootha VK. Walker MA, et al. Among authors: ludwig ls. N Engl J Med. 2020 Oct 15;383(16):1556-1563. doi: 10.1056/NEJMoa2001265. Epub 2020 Aug 12. N Engl J Med. 2020. PMID: 32786181 Free PMC article.
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling.
Lareau CA, Ludwig LS, Muus C, Gohil SH, Zhao T, Chiang Z, Pelka K, Verboon JM, Luo W, Christian E, Rosebrock D, Getz G, Boland GM, Chen F, Buenrostro JD, Hacohen N, Wu CJ, Aryee MJ, Regev A, Sankaran VG. Lareau CA, et al. Among authors: ludwig ls. Nat Biotechnol. 2021 Apr;39(4):451-461. doi: 10.1038/s41587-020-0645-6. Epub 2020 Aug 12. Nat Biotechnol. 2021. PMID: 32788668 Free PMC article.
47 results