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Antileishmanial Activities of (Z)-2-(Nitroimidazolylmethylene)-3(2H)-Benzofuranones: Synthesis, In Vitro Assessment, and Bioactivation by NTR 1 and 2.
Navidpour L, Lima ML, Milne R, Wyllie S, Hadj-Esfandiari N, Choudhary MI, Khan S, Yousuf S. Navidpour L, et al. Among authors: wyllie s. Antimicrob Agents Chemother. 2022 Nov 15;66(11):e0058322. doi: 10.1128/aac.00583-22. Epub 2022 Oct 26. Antimicrob Agents Chemother. 2022. PMID: 36286539 Free PMC article.
Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay.
De Rycker M, Hallyburton I, Thomas J, Campbell L, Wyllie S, Joshi D, Cameron S, Gilbert IH, Wyatt PG, Frearson JA, Fairlamb AH, Gray DW. De Rycker M, et al. Among authors: wyllie s. Antimicrob Agents Chemother. 2013 Jul;57(7):2913-22. doi: 10.1128/AAC.02398-12. Epub 2013 Apr 9. Antimicrob Agents Chemother. 2013. PMID: 23571538 Free PMC article.
Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei.
Wyllie S, Foth BJ, Kelner A, Sokolova AY, Berriman M, Fairlamb AH. Wyllie S, et al. J Antimicrob Chemother. 2016 Mar;71(3):625-34. doi: 10.1093/jac/dkv376. Epub 2015 Nov 17. J Antimicrob Chemother. 2016. PMID: 26581221 Free PMC article.
Antitrypanosomal 8-Hydroxy-Naphthyridines Are Chelators of Divalent Transition Metals.
Wall RJ, Moniz S, Thomas MG, Norval S, Ko EJ, Marco M, Miles TJ, Gilbert IH, Horn D, Fairlamb AH, Wyllie S. Wall RJ, et al. Among authors: wyllie s. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00235-18. doi: 10.1128/AAC.00235-18. Print 2018 Aug. Antimicrob Agents Chemother. 2018. PMID: 29844044 Free PMC article.
Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study.
Pedron J, Boudot C, Hutter S, Bourgeade-Delmas S, Stigliani JL, Sournia-Saquet A, Moreau A, Boutet-Robinet E, Paloque L, Mothes E, Laget M, Vendier L, Pratviel G, Wyllie S, Fairlamb A, Azas N, Courtioux B, Valentin A, Verhaeghe P. Pedron J, et al. Among authors: wyllie s. Eur J Med Chem. 2018 Jul 15;155:135-152. doi: 10.1016/j.ejmech.2018.06.001. Epub 2018 Jun 5. Eur J Med Chem. 2018. PMID: 29885575 Free PMC article.
Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani.
Corpas-Lopez V, Moniz S, Thomas M, Wall RJ, Torrie LS, Zander-Dinse D, Tinti M, Brand S, Stojanovski L, Manthri S, Hallyburton I, Zuccotto F, Wyatt PG, De Rycker M, Horn D, Ferguson MAJ, Clos J, Read KD, Fairlamb AH, Gilbert IH, Wyllie S. Corpas-Lopez V, et al. Among authors: wyllie s. ACS Infect Dis. 2019 Jan 11;5(1):111-122. doi: 10.1021/acsinfecdis.8b00226. Epub 2018 Nov 12. ACS Infect Dis. 2019. PMID: 30380837 Free PMC article.
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