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Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism.
Wang L, Mirabella VR, Dai R, Su X, Xu R, Jadali A, Bernabucci M, Singh I, Chen Y, Tian J, Jiang P, Kwan KY, Pak C, Liu C, Comoletti D, Hart RP, Chen C, Südhof TC, Pang ZP. Wang L, et al. Among authors: sudhof tc. Mol Psychiatry. 2022 Oct 24:10.1038/s41380-022-01834-x. doi: 10.1038/s41380-022-01834-x. Online ahead of print. Mol Psychiatry. 2022. PMID: 36280753 Free PMC article.
Engineered adhesion molecules drive synapse organization.
Hale WD, Südhof TC, Huganir RL. Hale WD, et al. Among authors: sudhof tc. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2215905120. doi: 10.1073/pnas.2215905120. Epub 2023 Jan 13. Proc Natl Acad Sci U S A. 2023. PMID: 36638214 Free PMC article.
656 results