Thomas R - Search Results

1

Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritis.

Sonigra A, Nel HJ, Wehr P, Ramnoruth N, Patel S, van Schie KA, Bladen MW, Mehdi AM, Tesiram J, Talekar M, Rossjohn J, Reid HH, Stuurman FE, Roberts H, Vecchio P, Gourley I, Rigby M, Becart S, Toes RE, Scherer HU, Lê Cao KA, Campbell K, Thomas R. Sonigra A, et al. Among authors: thomas r. JCI Insight. 2022 Oct 24;7(20):e160964. doi: 10.1172/jci.insight.160964. JCI Insight. 2022. PMID: 36278483 Free PMC article. Clinical Trial.

2

Cells of the synovium in rheumatoid arthritis. Dendritic cells.

Lutzky V, Hannawi S, Thomas R. Lutzky V, et al. Among authors: thomas r. Arthritis Res Ther. 2007;9(4):219. doi: 10.1186/ar2200. Arthritis Res Ther. 2007. PMID: 17850683 Free PMC article. Review.

3

High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?

Thomas R, Turner M, Cope AP. Thomas R, et al. Arthritis Res Ther. 2008;10(4):210. doi: 10.1186/ar2446. Epub 2008 Jul 24. Arthritis Res Ther. 2008. PMID: 18710589 Free PMC article. Review.

4

Antigen-specific suppression of inflammatory arthritis using liposomes.

Capini C, Jaturanpinyo M, Chang HI, Mutalik S, McNally A, Street S, Steptoe R, O'Sullivan B, Davies N, Thomas R. Capini C, et al. Among authors: thomas r. J Immunol. 2009 Mar 15;182(6):3556-65. doi: 10.4049/jimmunol.0802972. J Immunol. 2009. PMID: 19265134

5

T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles.

Law SC, Street S, Yu CH, Capini C, Ramnoruth S, Nel HJ, van Gorp E, Hyde C, Lau K, Pahau H, Purcell AW, Thomas R. Law SC, et al. Among authors: thomas r. Arthritis Res Ther. 2012 May 17;14(3):R118. doi: 10.1186/ar3848. Arthritis Res Ther. 2012. PMID: 22594821 Free PMC article.

6

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis.

Scally SW, Petersen J, Law SC, Dudek NL, Nel HJ, Loh KL, Wijeyewickrema LC, Eckle SB, van Heemst J, Pike RN, McCluskey J, Toes RE, La Gruta NL, Purcell AW, Reid HH, Thomas R, Rossjohn J. Scally SW, et al. Among authors: thomas r. J Exp Med. 2013 Nov 18;210(12):2569-82. doi: 10.1084/jem.20131241. Epub 2013 Nov 4. J Exp Med. 2013. PMID: 24190431 Free PMC article.

7

Identification of self-antigen-specific T cells reflecting loss of tolerance in autoimmune disease underpins preventative immunotherapeutic strategies in rheumatoid arthritis.

Law SC, Benham H, Reid HH, Rossjohn J, Thomas R. Law SC, et al. Among authors: thomas r. Rheum Dis Clin North Am. 2014 Nov;40(4):735-52. doi: 10.1016/j.rdc.2014.07.015. Epub 2014 Sep 2. Rheum Dis Clin North Am. 2014. PMID: 25437289 Review.

8

IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis.

Anderson AE, Pratt AG, Sedhom MA, Doran JP, Routledge C, Hargreaves B, Brown PM, Lê Cao KA, Isaacs JD, Thomas R. Anderson AE, et al. Among authors: thomas r. Ann Rheum Dis. 2016 Feb;75(2):466-73. doi: 10.1136/annrheumdis-2014-205850. Epub 2015 Feb 3. Ann Rheum Dis. 2016. PMID: 25649145 Free PMC article.

9

Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens.

Koning F, Thomas R, Rossjohn J, Toes RE. Koning F, et al. Among authors: thomas r. Nat Rev Rheumatol. 2015 Aug;11(8):450-61. doi: 10.1038/nrrheum.2015.59. Epub 2015 May 19. Nat Rev Rheumatol. 2015. PMID: 25986717 Review.

10

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype-positive rheumatoid arthritis patients.

Benham H, Nel HJ, Law SC, Mehdi AM, Street S, Ramnoruth N, Pahau H, Lee BT, Ng J, Brunck ME, Hyde C, Trouw LA, Dudek NL, Purcell AW, O'Sullivan BJ, Connolly JE, Paul SK, Lê Cao KA, Thomas R. Benham H, et al. Among authors: thomas r. Sci Transl Med. 2015 Jun 3;7(290):290ra87. doi: 10.1126/scitranslmed.aaa9301. Sci Transl Med. 2015. PMID: 26041704

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