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A predictive computational framework for direct reprogramming between human cell types.
Rackham OJ, Firas J, Fang H, Oates ME, Holmes ML, Knaupp AS; FANTOM Consortium; Suzuki H, Nefzger CM, Daub CO, Shin JW, Petretto E, Forrest AR, Hayashizaki Y, Polo JM, Gough J. Rackham OJ, et al. Nat Genet. 2016 Mar;48(3):331-5. doi: 10.1038/ng.3487. Epub 2016 Jan 18. Nat Genet. 2016. PMID: 26780608 Free article.
Computational methods for direct cell conversion.
Kamaraj US, Gough J, Polo JM, Petretto E, Rackham OJ. Kamaraj US, et al. Cell Cycle. 2016 Dec 16;15(24):3343-3354. doi: 10.1080/15384101.2016.1238119. Epub 2016 Oct 13. Cell Cycle. 2016. PMID: 27736295 Free PMC article. Review.
Cell Type of Origin Dictates the Route to Pluripotency.
Nefzger CM, Rossello FJ, Chen J, Liu X, Knaupp AS, Firas J, Paynter JM, Pflueger J, Buckberry S, Lim SM, Williams B, Alaei S, Faye-Chauhan K, Petretto E, Nilsson SK, Lister R, Ramialison M, Powell DR, Rackham OJL, Polo JM. Nefzger CM, et al. Among authors: rackham ojl. Cell Rep. 2017 Dec 5;21(10):2649-2660. doi: 10.1016/j.celrep.2017.11.029. Cell Rep. 2017. PMID: 29212013 Free article.
Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins.
Chothani S, Schäfer S, Adami E, Viswanathan S, Widjaja AA, Langley SR, Tan J, Wang M, Quaife NM, Jian Pua C, D'Agostino G, Guna Shekeran S, George BL, Lim S, Yiqun Cao E, van Heesch S, Witte F, Felkin LE, Christodoulou EG, Dong J, Blachut S, Patone G, Barton PJR, Hubner N, Cook SA, Rackham OJL. Chothani S, et al. Among authors: rackham ojl. Circulation. 2019 Sep 10;140(11):937-951. doi: 10.1161/CIRCULATIONAHA.119.039596. Epub 2019 Jul 9. Circulation. 2019. PMID: 31284728 Free PMC article.
WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling.
Chen H, Moreno-Moral A, Pesce F, Devapragash N, Mancini M, Heng EL, Rotival M, Srivastava PK, Harmston N, Shkura K, Rackham OJL, Yu WP, Sun XM, Tee NGZ, Tan ELS, Barton PJR, Felkin LE, Lara-Pezzi E, Angelini G, Beltrami C, Pravenec M, Schafer S, Bottolo L, Hubner N, Emanueli C, Cook SA, Petretto E. Chen H, et al. Among authors: rackham ojl. Nat Commun. 2019 Aug 9;10(1):3616. doi: 10.1038/s41467-019-11551-9. Nat Commun. 2019. PMID: 31399586 Free PMC article.
70 results