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Epstein Barr virus-mediated transformation of B cells from XIAP-deficient patients leads to increased expression of the tumor suppressor CADM1.
Cell Death Dis. 2022 Oct 22;13(10):892. doi: 10.1038/s41419-022-05337-z.
Cell Death Dis. 2022.
PMID: 36270981
Free PMC article.
Modification of EBV Associated Lymphomagenesis and Its Immune Control by Co-Infections and Genetics in Humanized Mice.
Schuhmachers P, Münz C.
Schuhmachers P, et al.
Front Immunol. 2021 Mar 23;12:640918. doi: 10.3389/fimmu.2021.640918. eCollection 2021.
Front Immunol. 2021.
PMID: 33833760
Free PMC article.
Review.
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CD27 is required for protective lytic EBV antigen-specific CD8+ T-cell expansion.
Deng Y, Chatterjee B, Zens K, Zdimerova H, Müller A, Schuhmachers P, Ligeon LA, Bongiovanni A, Capaul R, Zbinden A, Holler A, Stauss H, Hammerschmidt W, Münz C.
Deng Y, et al. Among authors: schuhmachers p.
Blood. 2021 Jun 10;137(23):3225-3236. doi: 10.1182/blood.2020009482.
Blood. 2021.
PMID: 33827115
Free PMC article.
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PLK1-dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV-infected mice.
Zhang X, Schuhmachers P, Mourão A, Giansanti P, Murer A, Thumann S, Kuklik-Roos C, Beer S, Hauck SM, Hammerschmidt W, Küppers R, Kuster B, Raab M, Strebhardt K, Sattler M, Münz C, Kempkes B.
Zhang X, et al. Among authors: schuhmachers p.
EMBO Rep. 2021 Dec 6;22(12):e53007. doi: 10.15252/embr.202153007. Epub 2021 Oct 4.
EMBO Rep. 2021.
PMID: 34605140
Free PMC article.
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A metabolic dependency of EBV can be targeted to hinder B cell transformation.
Müller-Durovic B, Jäger J, Engelmann C, Schuhmachers P, Altermatt S, Schlup Y, Duthaler U, Makowiec C, Unterstab G, Roffeis S, Xhafa E, Assmann N, Trulsson F, Steiner R, Edwards-Hicks J, West J, Turner L, Develioglu L, Ivanek R, Azzi T, Dehio P, Berger C; Swiss Transplant Cohort Study#; Kuzmin D, Saboz S, Mautner J, Löliger J, Geigges M, Palianina D, Khanna N, Dirnhofer S, Münz C, Bantug GR, Hess C.
Müller-Durovic B, et al. Among authors: schuhmachers p.
Science. 2024 May 23:eadk4898. doi: 10.1126/science.adk4898. Online ahead of print.
Science. 2024.
PMID: 38781354
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MHC class II-deficient mice allow functional human CD4+ T-cell development.
Läderach F, Zdimerova H, Rieble L, Schuhmachers P, Engelmann C, Valencia-Camargo AD, Kirchmeier D, Böni M, Münz C.
Läderach F, et al. Among authors: schuhmachers p.
Eur J Immunol. 2023 Jul;53(7):e2250313. doi: 10.1002/eji.202250313. Epub 2023 May 12.
Eur J Immunol. 2023.
PMID: 37118896
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