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Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.
Maity-Kumar G, Ständer L, DeAngelis M, Lee S, Molenaar A, Becker L, Garrett L, Amerie OV, Hoelter SM, Wurst W, Fuchs H, Feuchtinger A, Gailus-Durner V, Garcia-Caceres C, Othman AE, Brockmann C, Schöffling VI, Beiser K, Krude H, Mroz PA, Hofmann S, Tuckermann J, DiMarchi RD, Hrabe de Angelis M, Tschöp MH, Pfluger PT, Müller TD. Maity-Kumar G, et al. Mol Metab. 2022 Dec;66:101616. doi: 10.1016/j.molmet.2022.101616. Epub 2022 Oct 18. Mol Metab. 2022. PMID: 36270613 Free PMC article.
Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity.
Horvath TL, Sarman B, García-Cáceres C, Enriori PJ, Sotonyi P, Shanabrough M, Borok E, Argente J, Chowen JA, Perez-Tilve D, Pfluger PT, Brönneke HS, Levin BE, Diano S, Cowley MA, Tschöp MH. Horvath TL, et al. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14875-80. doi: 10.1073/pnas.1004282107. Epub 2010 Aug 2. Proc Natl Acad Sci U S A. 2010. PMID: 20679202 Free PMC article.
Targeted estrogen delivery reverses the metabolic syndrome.
Finan B, Yang B, Ottaway N, Stemmer K, Müller TD, Yi CX, Habegger K, Schriever SC, García-Cáceres C, Kabra DG, Hembree J, Holland J, Raver C, Seeley RJ, Hans W, Irmler M, Beckers J, de Angelis MH, Tiano JP, Mauvais-Jarvis F, Perez-Tilve D, Pfluger P, Zhang L, Gelfanov V, DiMarchi RD, Tschöp MH. Finan B, et al. Nat Med. 2012 Dec;18(12):1847-56. doi: 10.1038/nm.3009. Epub 2012 Nov 11. Nat Med. 2012. PMID: 23142820 Free PMC article.
Hypothalamic astrocytes in obesity.
García-Cáceres C, Yi CX, Tschöp MH. García-Cáceres C, et al. Endocrinol Metab Clin North Am. 2013 Mar;42(1):57-66. doi: 10.1016/j.ecl.2012.11.003. Epub 2012 Dec 12. Endocrinol Metab Clin North Am. 2013. PMID: 23391239 Review.
Estrogen, astrocytes and the neuroendocrine control of metabolism.
Fuente-Martin E, Garcia-Caceres C, Morselli E, Clegg DJ, Chowen JA, Finan B, Brinton RD, Tschöp MH. Fuente-Martin E, et al. Rev Endocr Metab Disord. 2013 Dec;14(4):331-8. doi: 10.1007/s11154-013-9263-7. Rev Endocr Metab Disord. 2013. PMID: 24009071 Free PMC article. Review.
The emerging neurobiology of calorie addiction.
García-Cáceres C, Tschöp MH. García-Cáceres C, et al. Elife. 2014;3:e01928. doi: 10.7554/eLife.01928. Epub 2014 Jan 7. Elife. 2014. PMID: 24399459 Free PMC article.
Hypothalamic Injury: Fish Oil to the Rescue!
García-Cáceres C, Tschöp MH. García-Cáceres C, et al. Diabetes. 2016 Mar;65(3):551-3. doi: 10.2337/dbi15-0036. Diabetes. 2016. PMID: 26908906 No abstract available.
Hypothalamic leptin action is mediated by histone deacetylase 5.
Kabra DG, Pfuhlmann K, García-Cáceres C, Schriever SC, Casquero García V, Kebede AF, Fuente-Martin E, Trivedi C, Heppner K, Uhlenhaut NH, Legutko B, Kabra UD, Gao Y, Yi CX, Quarta C, Clemmensen C, Finan B, Müller TD, Meyer CW, Paez-Pereda M, Stemmer K, Woods SC, Perez-Tilve D, Schneider R, Olson EN, Tschöp MH, Pfluger PT. Kabra DG, et al. Nat Commun. 2016 Feb 29;7:10782. doi: 10.1038/ncomms10782. Nat Commun. 2016. PMID: 26923837 Free PMC article.
Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability.
García-Cáceres C, Quarta C, Varela L, Gao Y, Gruber T, Legutko B, Jastroch M, Johansson P, Ninkovic J, Yi CX, Le Thuc O, Szigeti-Buck K, Cai W, Meyer CW, Pfluger PT, Fernandez AM, Luquet S, Woods SC, Torres-Alemán I, Kahn CR, Götz M, Horvath TL, Tschöp MH. García-Cáceres C, et al. Cell. 2016 Aug 11;166(4):867-880. doi: 10.1016/j.cell.2016.07.028. Cell. 2016. PMID: 27518562 Free PMC article.
TNFα drives mitochondrial stress in POMC neurons in obesity.
Yi CX, Walter M, Gao Y, Pitra S, Legutko B, Kälin S, Layritz C, García-Cáceres C, Bielohuby M, Bidlingmaier M, Woods SC, Ghanem A, Conzelmann KK, Stern JE, Jastroch M, Tschöp MH. Yi CX, et al. Nat Commun. 2017 May 10;8:15143. doi: 10.1038/ncomms15143. Nat Commun. 2017. PMID: 28489068 Free PMC article.
73 results