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Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2.
Shi G, Chiramel AI, Li T, Lai KK, Kenney AD, Zani A, Eddy AC, Majdoul S, Zhang L, Dempsey T, Beare PA, Kar S, Yewdell JW, Best SM, Yount JS, Compton AA. Shi G, et al. Among authors: best sm. J Clin Invest. 2022 Dec 15;132(24):e160766. doi: 10.1172/JCI160766. J Clin Invest. 2022. PMID: 36264642 Free PMC article.
Flavivirus Antagonism of Type I Interferon Signaling Reveals Prolidase as a Regulator of IFNAR1 Surface Expression.
Lubick KJ, Robertson SJ, McNally KL, Freedman BA, Rasmussen AL, Taylor RT, Walts AD, Tsuruda S, Sakai M, Ishizuka M, Boer EF, Foster EC, Chiramel AI, Addison CB, Green R, Kastner DL, Katze MG, Holland SM, Forlino A, Freeman AF, Boehm M, Yoshii K, Best SM. Lubick KJ, et al. Among authors: best sm. Cell Host Microbe. 2015 Jul 8;18(1):61-74. doi: 10.1016/j.chom.2015.06.007. Cell Host Microbe. 2015. PMID: 26159719 Free PMC article.
A Systems Approach Reveals MAVS Signaling in Myeloid Cells as Critical for Resistance to Ebola Virus in Murine Models of Infection.
Dutta M, Robertson SJ, Okumura A, Scott DP, Chang J, Weiss JM, Sturdevant GL, Feldmann F, Haddock E, Chiramel AI, Ponia SS, Dougherty JD, Katze MG, Rasmussen AL, Best SM. Dutta M, et al. Among authors: best sm. Cell Rep. 2017 Jan 17;18(3):816-829. doi: 10.1016/j.celrep.2016.12.069. Cell Rep. 2017. PMID: 28099857 Free PMC article.
Role of autophagy in Zika virus infection and pathogenesis.
Chiramel AI, Best SM. Chiramel AI, et al. Among authors: best sm. Virus Res. 2018 Aug 2;254:34-40. doi: 10.1016/j.virusres.2017.09.006. Epub 2017 Sep 9. Virus Res. 2018. PMID: 28899653 Free PMC article. Review.
A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle.
Martin S, Chiramel AI, Schmidt ML, Chen YC, Whitt N, Watt A, Dunham EC, Shifflett K, Traeger S, Leske A, Buehler E, Martellaro C, Brandt J, Wendt L, Müller A, Peitsch S, Best SM, Stech J, Finke S, Römer-Oberdörfer A, Groseth A, Feldmann H, Hoenen T. Martin S, et al. Among authors: best sm. Genome Med. 2018 Aug 7;10(1):58. doi: 10.1186/s13073-018-0570-1. Genome Med. 2018. PMID: 30081931 Free PMC article.
TRIM5α Restricts Flavivirus Replication by Targeting the Viral Protease for Proteasomal Degradation.
Chiramel AI, Meyerson NR, McNally KL, Broeckel RM, Montoya VR, Méndez-Solís O, Robertson SJ, Sturdevant GL, Lubick KJ, Nair V, Youseff BH, Ireland RM, Bosio CM, Kim K, Luban J, Hirsch VM, Taylor RT, Bouamr F, Sawyer SL, Best SM. Chiramel AI, et al. Among authors: best sm. Cell Rep. 2019 Jun 11;27(11):3269-3283.e6. doi: 10.1016/j.celrep.2019.05.040. Cell Rep. 2019. PMID: 31189110 Free PMC article.
239 results