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BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER.
Schäuble N, Lang S, Jung M, Cappel S, Schorr S, Ulucan Ö, Linxweiler J, Dudek J, Blum R, Helms V, Paton AW, Paton JC, Cavalié A, Zimmermann R. Schäuble N, et al. Among authors: zimmermann r. EMBO J. 2012 Aug 1;31(15):3282-96. doi: 10.1038/emboj.2012.189. Epub 2012 Jul 13. EMBO J. 2012. PMID: 22796945 Free PMC article.
Targeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells.
Linxweiler M, Schorr S, Schäuble N, Jung M, Linxweiler J, Langer F, Schäfers HJ, Cavalié A, Zimmermann R, Greiner M. Linxweiler M, et al. Among authors: zimmermann r. BMC Cancer. 2013 Dec 5;13:574. doi: 10.1186/1471-2407-13-574. BMC Cancer. 2013. PMID: 24304694 Free PMC article.
An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases.
Lang S, Pfeffer S, Lee PH, Cavalié A, Helms V, Förster F, Zimmermann R. Lang S, et al. Among authors: zimmermann r. Front Physiol. 2017 Nov 1;8:887. doi: 10.3389/fphys.2017.00887. eCollection 2017. Front Physiol. 2017. PMID: 29163222 Free PMC article. Review.
Treatment of SEC62 over-expressing tumors by Thapsigargin and Trifluoperazine.
Körbel C, Linxweiler M, Bochen F, Wemmert S, Schick B, Meyer M, Maurer H, Menger MD, Zimmermann R, Greiner M. Körbel C, et al. Among authors: zimmermann r. Biomol Concepts. 2018 May 19;9(1):53-63. doi: 10.1515/bmc-2018-0006. Biomol Concepts. 2018. PMID: 29779013 Free article.
2,056 results