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Disruption of proteostasis causes IRE1 mediated reprogramming of alveolar epithelial cells.
Katzen J, Rodriguez L, Tomer Y, Babu A, Zhao M, Murthy A, Carson P, Barrett M, Basil MC, Carl J, Leach JP, Morley M, McGraw MD, Mulugeta S, Pelura T, Rosen G, Morrisey EE, Beers MF. Katzen J, et al. Among authors: zhao m. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2123187119. doi: 10.1073/pnas.2123187119. Epub 2022 Oct 17. Proc Natl Acad Sci U S A. 2022. PMID: 36252035 Free PMC article.
The common ABCA3E292V variant disrupts AT2 cell quality control and increases susceptibility to lung injury and aberrant remodeling.
Tomer Y, Wambach J, Knudsen L, Zhao M, Rodriguez LR, Murthy A, White FV, Venosa A, Katzen J, Ochs M, Hamvas A, Beers MF, Mulugeta S. Tomer Y, et al. Among authors: zhao m. Am J Physiol Lung Cell Mol Physiol. 2021 Aug 1;321(2):L291-L307. doi: 10.1152/ajplung.00400.2020. Epub 2021 Jun 16. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 34132118 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35556348
ABCA3 is critical for lamellar body biogenesis in vivo.
Cheong N, Zhang H, Madesh M, Zhao M, Yu K, Dodia C, Fisher AB, Savani RC, Shuman H. Cheong N, et al. Among authors: zhao m. J Biol Chem. 2007 Aug 17;282(33):23811-7. doi: 10.1074/jbc.M703927200. Epub 2007 May 31. J Biol Chem. 2007. PMID: 17540762 Free article.
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