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Page 1
Silver Nanoparticles Stabilized by Poly (Vinyl Pyrrolidone) with Potential Anticancer Activity towards Prostate Cancer.
Abdellatif AAH, Abdelfattah A, Bouazzaoui A, Osman SK, Al-Moraya IS, Showail AMS, Alsharidah M, Aboelela A, Al Rugaie O, Faris TM, Tawfeek HM. Abdellatif AAH, et al. Among authors: aboelela a. Bioinorg Chem Appl. 2022 Sep 30;2022:6181448. doi: 10.1155/2022/6181448. eCollection 2022. Bioinorg Chem Appl. 2022. PMID: 36248627 Free PMC article. Retracted.
6-Furopyridine Hexamethylene Amiloride Is a Non-Selective P2X7 Receptor Antagonist.
Cuthbertson P, Elhage A, Al-Rifai D, Sophocleous RA, Turner RJ, Aboelela A, Majed H, Bujaroski RS, Jalilian I, Kelso MJ, Watson D, Buckley BJ, Sluyter R. Cuthbertson P, et al. Among authors: aboelela a. Biomolecules. 2022 Sep 16;12(9):1309. doi: 10.3390/biom12091309. Biomolecules. 2022. PMID: 36139148 Free PMC article.
6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
Buckley BJ, Aboelela A, Minaei E, Jiang LX, Xu Z, Ali U, Fildes K, Cheung CY, Cook SM, Johnson DC, Bachovchin DA, Cook GM, Apte M, Huang M, Ranson M, Kelso MJ. Buckley BJ, et al. Among authors: aboelela a. J Med Chem. 2018 Sep 27;61(18):8299-8320. doi: 10.1021/acs.jmedchem.8b00838. Epub 2018 Sep 7. J Med Chem. 2018. PMID: 30130401 Free PMC article.
6-Substituted amiloride derivatives as inhibitors of the urokinase-type plasminogen activator for use in metastatic disease.
Buckley BJ, Majed H, Aboelela A, Minaei E, Jiang L, Fildes K, Cheung CY, Johnson D, Bachovchin D, Cook GM, Huang M, Ranson M, Kelso MJ. Buckley BJ, et al. Among authors: aboelela a. Bioorg Med Chem Lett. 2019 Dec 15;29(24):126753. doi: 10.1016/j.bmcl.2019.126753. Epub 2019 Oct 28. Bioorg Med Chem Lett. 2019. PMID: 31679971 Free PMC article.
Systematic evaluation of structure-property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride.
Buckley BJ, Aboelela A, Majed H, Bujaroski RS, White KL, Powell AK, Wang W, Katneni K, Saunders J, Shackleford DM, Charman SA, Cook GM, Kelso MJ, Ranson M. Buckley BJ, et al. Among authors: aboelela a. Bioorg Med Chem. 2021 May 1;37:116116. doi: 10.1016/j.bmc.2021.116116. Epub 2021 Mar 23. Bioorg Med Chem. 2021. PMID: 33799173
Automated Patch Clamp Screening of Amiloride and 5-N,N-Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor.
Finol-Urdaneta RK, McArthur JR, Aboelela A, Bujaroski RS, Majed H, Rangel A, Adams DJ, Ranson M, Kelso MJ, Buckley BJ. Finol-Urdaneta RK, et al. Among authors: aboelela a. Mol Pharm. 2023 Jul 3;20(7):3367-3379. doi: 10.1021/acs.molpharmaceut.2c01083. Epub 2023 Jun 1. Mol Pharm. 2023. PMID: 37260417
A dual-targeting succinate dehydrogenase and F1Fo-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis.
Adolph C, Cheung CY, McNeil MB, Jowsey WJ, Williams ZC, Hards K, Harold LK, Aboelela A, Bujaroski RS, Buckley BJ, Tyndall JDA, Li Z, Langer JD, Preiss L, Meier T, Steyn AJC, Rhee KY, Berney M, Kelso MJ, Cook GM. Adolph C, et al. Among authors: aboelela a. Cell Chem Biol. 2024 Apr 18;31(4):683-698.e7. doi: 10.1016/j.chembiol.2023.12.002. Epub 2023 Dec 26. Cell Chem Biol. 2024. PMID: 38151019
16 results