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Stable nebulization and muco-trapping properties of regdanvimab/IN-006 support its development as a potent, dose-saving inhaled therapy for COVID-19.
McSweeney MD, Stewart I, Richardson Z, Kang H, Park Y, Kim C, Tiruthani K, Wolf W, Schaefer A, Kumar P, Aurora H, Hutchins J, Cho JM, Hickey AJ, Lee SY, Lai SK. McSweeney MD, et al. Bioeng Transl Med. 2022 Aug 30;8(1):e10391. doi: 10.1002/btm2.10391. Online ahead of print. Bioeng Transl Med. 2022. PMID: 36248234 Free PMC article.
Overcoming anti-PEG antibody mediated accelerated blood clearance of PEGylated liposomes by pre-infusion with high molecular weight free PEG.
McSweeney MD, Price LSL, Wessler T, Ciociola EC, Herity LB, Piscitelli JA, DeWalle AC, Harris TN, Chan AKP, Saw RS, Hu P, Jennette JC, Forest MG, Cao Y, Montgomery SA, Zamboni WC, Lai SK. McSweeney MD, et al. J Control Release. 2019 Oct;311-312:138-146. doi: 10.1016/j.jconrel.2019.08.017. Epub 2019 Aug 24. J Control Release. 2019. PMID: 31454530 Free PMC article.
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