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A combination of novel NSC small molecule inhibitor along with doxorubicin inhibits proliferation of triple-negative breast cancer through metabolic reprogramming.
Yousefi H, Khosla M, Lauterboeck L, Okpechi SC, Worthylake D, Garai J, Zabaleta J, Guidry J, Zarandi MA, Wyczechowska D, Jayawickramarajah J, Yang Q, Kissil J, Alahari SK. Yousefi H, et al. Among authors: kissil j. Oncogene. 2022 Nov;41(47):5076-5091. doi: 10.1038/s41388-022-02497-2. Epub 2022 Oct 15. Oncogene. 2022. PMID: 36243802
The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis.
Zhou C, Licciulli S, Avila JL, Cho M, Troutman S, Jiang P, Kossenkov AV, Showe LC, Liu Q, Vachani A, Albelda SM, Kissil JL. Zhou C, et al. Among authors: kissil jl. Oncogene. 2013 Feb 14;32(7):903-9. doi: 10.1038/onc.2012.99. Epub 2012 Mar 19. Oncogene. 2013. PMID: 22430205 Free PMC article.
FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas.
Licciulli S, Maksimoska J, Zhou C, Troutman S, Kota S, Liu Q, Duron S, Campbell D, Chernoff J, Field J, Marmorstein R, Kissil JL. Licciulli S, et al. Among authors: kissil jl. J Biol Chem. 2013 Oct 4;288(40):29105-14. doi: 10.1074/jbc.M113.510933. Epub 2013 Aug 19. J Biol Chem. 2013. PMID: 23960073 Free PMC article.
64 results