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Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity.
Sci Immunol. 2022 Oct 21;7(76):eabo3420. doi: 10.1126/sciimmunol.abo3420. Epub 2022 Oct 14.
Sci Immunol. 2022.
PMID: 36240285
Free PMC article.
TIGIT inhibition and lenalidomide synergistically promote antimyeloma immune responses after stem cell transplantation in mice.
Minnie SA, Waltner OG, Ensbey KS, Olver SD, Collinge AD, Sester DP, Schmidt CR, Legg SR, Takahashi S, Nemychenkov NS, Sekiguchi T, Driessens G, Zhang P, Koyama M, Spencer A, Holmberg LA, Furlan SN, Varelias A, Hill GR.
Minnie SA, et al. Among authors: nemychenkov ns.
J Clin Invest. 2023 Feb 15;133(4):e157907. doi: 10.1172/JCI157907.
J Clin Invest. 2023.
PMID: 36512425
Free PMC article.
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Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD.
Wang Y, Ullah MA, Waltner OG, Bhise SS, Ensbey KS, Schmidt CR, Legg SR, Sekiguchi T, Nelson EL, Kuns RD, Nemychenkov NS, Atilla E, Yeh AC, Takahashi S, Boiko JR, Varelias A, Blazar BR, Koyama M, Minnie SA, Clouston AD, Furlan SN, Zhang P, Hill GR.
Wang Y, et al. Among authors: nemychenkov ns.
J Clin Invest. 2024 Jun 3;134(11):e170125. doi: 10.1172/JCI170125.
J Clin Invest. 2024.
PMID: 38828727
Free PMC article.
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TIM-3+ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies.
Minnie SA, Waltner OG, Zhang P, Takahashi S, Nemychenkov NS, Ensbey KS, Schmidt CR, Legg SRW, Comstock M, Boiko JR, Nelson E, Bhise SS, Wilkens AB, Koyama M, Dhodapkar MV, Chesi M, Riddell SR, Green DJ, Spencer A, Furlan SN, Hill GR.
Minnie SA, et al. Among authors: nemychenkov ns.
Sci Immunol. 2024 Apr 19;9(94):eadg1094. doi: 10.1126/sciimmunol.adg1094. Epub 2024 Apr 19.
Sci Immunol. 2024.
PMID: 38640253
Free PMC article.
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