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Plasma Lipidomic Profiles Improve on Traditional Risk Factors for the Prediction of Cardiovascular Events in Type 2 Diabetes Mellitus.
Alshehry ZH, Mundra PA, Barlow CK, Mellett NA, Wong G, McConville MJ, Simes J, Tonkin AM, Sullivan DR, Barnes EH, Nestel PJ, Kingwell BA, Marre M, Neal B, Poulter NR, Rodgers A, Williams B, Zoungas S, Hillis GS, Chalmers J, Woodward M, Meikle PJ. Alshehry ZH, et al. Among authors: meikle pj. Circulation. 2016 Nov 22;134(21):1637-1650. doi: 10.1161/CIRCULATIONAHA.116.023233. Epub 2016 Oct 18. Circulation. 2016. PMID: 27756783 Free article. Clinical Trial.
Large-scale plasma lipidomic profiling identifies lipids that predict cardiovascular events in secondary prevention.
Mundra PA, Barlow CK, Nestel PJ, Barnes EH, Kirby A, Thompson P, Sullivan DR, Alshehry ZH, Mellett NA, Huynh K, Jayawardana KS, Giles C, McConville MJ, Zoungas S, Hillis GS, Chalmers J, Woodward M, Wong G, Kingwell BA, Simes J, Tonkin AM, Meikle PJ; LIPID Study Investigators. Mundra PA, et al. Among authors: meikle pj. JCI Insight. 2018 Sep 6;3(17):e121326. doi: 10.1172/jci.insight.121326. eCollection 2018 Sep 6. JCI Insight. 2018. PMID: 30185661 Free PMC article.
Changes in plasma lipids predict pravastatin efficacy in secondary prevention.
Jayawardana KS, Mundra PA, Giles C, Barlow CK, Nestel PJ, Barnes EH, Kirby A, Thompson P, Sullivan DR, Alshehry ZH, Mellett NA, Huynh K, McConville MJ, Zoungas S, Hillis GS, Chalmers J, Woodward M, Marschner IC, Wong G, Kingwell BA, Simes J, Tonkin AM, Meikle PJ; LIPID Study Investigators. Jayawardana KS, et al. Among authors: meikle pj. JCI Insight. 2019 Jul 11;4(13):e128438. doi: 10.1172/jci.insight.128438. eCollection 2019 Jul 11. JCI Insight. 2019. PMID: 31292301 Free PMC article. Clinical Trial.
Insulin signaling requires glucose to promote lipid anabolism in adipocytes.
Krycer JR, Quek LE, Francis D, Zadoorian A, Weiss FC, Cooke KC, Nelson ME, Diaz-Vegas A, Humphrey SJ, Scalzo R, Hirayama A, Ikeda S, Shoji F, Suzuki K, Huynh K, Giles C, Varney B, Nagarajan SR, Hoy AJ, Soga T, Meikle PJ, Cooney GJ, Fazakerley DJ, James DE. Krycer JR, et al. Among authors: meikle pj. J Biol Chem. 2020 Sep 18;295(38):13250-13266. doi: 10.1074/jbc.RA120.014907. Epub 2020 Jul 28. J Biol Chem. 2020. PMID: 32723868 Free PMC article.
Aberrations in circulating ceramide levels are associated with poor clinical outcomes across localised and metastatic prostate cancer.
Lin HM, Huynh K, Kohli M, Tan W, Azad AA, Yeung N, Mahon KL, Mak B, Sutherland PD, Shepherd A, Mellett N, Docanto M, Giles C, Centenera MM, Butler LM, Meikle PJ, Horvath LG. Lin HM, et al. Among authors: meikle pj. Prostate Cancer Prostatic Dis. 2021 Sep;24(3):860-870. doi: 10.1038/s41391-021-00338-z. Epub 2021 Mar 21. Prostate Cancer Prostatic Dis. 2021. PMID: 33746214 Free PMC article.
Relationship between Circulating Lipids and Cytokines in Metastatic Castration-Resistant Prostate Cancer.
Lin HM, Yeung N, Hastings JF, Croucher DR, Huynh K, Meikle TG, Mellett NA, Kwan EM, Davis ID, Tran B, Mahon KL, Zhang A, Stockler MR, Briscoe K, Marx G, Bastick P, Crumbaker ML, Joshua AM, Azad AA, Meikle PJ, Horvath LG. Lin HM, et al. Among authors: meikle pj, meikle tg. Cancers (Basel). 2021 Oct 1;13(19):4964. doi: 10.3390/cancers13194964. Cancers (Basel). 2021. PMID: 34638448 Free PMC article.
Overcoming enzalutamide resistance in metastatic prostate cancer by targeting sphingosine kinase.
Lin HM, Mak B, Yeung N, Huynh K, Meikle TG, Mellett NA, Kwan EM, Fettke H, Tran B, Davis ID, Mahon KL, Zhang A, Stockler MR, Briscoe K, Marx G, Crumbaker M, Stricker PD, Du P, Yu J, Jia S, Scheinberg T, Fitzpatrick M, Bonnitcha P, Sullivan DR, Joshua AM, Azad AA, Butler LM, Meikle PJ, Horvath LG. Lin HM, et al. Among authors: meikle pj, meikle tg. EBioMedicine. 2021 Oct;72:103625. doi: 10.1016/j.ebiom.2021.103625. Epub 2021 Oct 14. EBioMedicine. 2021. PMID: 34656931 Free PMC article.
323 results