Kastner DL - Search Results

1

Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism.

Magnotti F, Chirita D, Dalmon S, Martin A, Bronnec P, Sousa J, Helynck O, Lee W, Kastner DL, Chae JJ, McDermott MF, Belot A, Popoff M, Sève P, Georgin-Lavialle S, Munier-Lehmann H, Tran TA, De Langhe E, Wouters C, Jamilloux Y, Henry T. Magnotti F, et al. Among authors: kastner dl. Cell Rep. 2022 Oct 11;41(2):111472. doi: 10.1016/j.celrep.2022.111472. Cell Rep. 2022. PMID: 36223753 Free PMC article.

2

Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes.

McDermott MF, Aksentijevich I, Galon J, McDermott EM, Ogunkolade BW, Centola M, Mansfield E, Gadina M, Karenko L, Pettersson T, McCarthy J, Frucht DM, Aringer M, Torosyan Y, Teppo AM, Wilson M, Karaarslan HM, Wan Y, Todd I, Wood G, Schlimgen R, Kumarajeewa TR, Cooper SM, Vella JP, Amos CI, Mulley J, Quane KA, Molloy MG, Ranki A, Powell RJ, Hitman GA, O'Shea JJ, Kastner DL. McDermott MF, et al. Among authors: kastner dl. Cell. 1999 Apr 2;97(1):133-44. doi: 10.1016/s0092-8674(00)80721-7. Cell. 1999. PMID: 10199409 Free article.

3

Isolation, genomic organization, and expression analysis of the mouse and rat homologs of MEFV, the gene for familial mediterranean fever.

Chae JJ, Centola M, Aksentijevich I, Dutra A, Tran M, Wood G, Nagaraju K, Kingma DW, Liu PP, Kastner DL. Chae JJ, et al. Among authors: kastner dl. Mamm Genome. 2000 Jun;11(6):428-35. doi: 10.1007/s003350010082. Mamm Genome. 2000. PMID: 10818206

4

TNFRSF1A mutations and autoinflammatory syndromes.

Galon J, Aksentijevich I, McDermott MF, O'Shea JJ, Kastner DL. Galon J, et al. Among authors: kastner dl. Curr Opin Immunol. 2000 Aug;12(4):479-86. doi: 10.1016/s0952-7915(00)00124-2. Curr Opin Immunol. 2000. PMID: 10899034 Review.

5

The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments.

Mansfield E, Chae JJ, Komarow HD, Brotz TM, Frucht DM, Aksentijevich I, Kastner DL. Mansfield E, et al. Among authors: kastner dl. Blood. 2001 Aug 1;98(3):851-9. doi: 10.1182/blood.v98.3.851. Blood. 2001. PMID: 11468188 Free article.

6

The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations.

Hull KM, Shoham N, Chae JJ, Aksentijevich I, Kastner DL. Hull KM, et al. Among authors: kastner dl. Curr Opin Rheumatol. 2003 Jan;15(1):61-9. doi: 10.1097/00002281-200301000-00011. Curr Opin Rheumatol. 2003. PMID: 12496512 Review.

7

Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis.

Chae JJ, Komarow HD, Cheng J, Wood G, Raben N, Liu PP, Kastner DL. Chae JJ, et al. Among authors: kastner dl. Mol Cell. 2003 Mar;11(3):591-604. doi: 10.1016/s1097-2765(03)00056-x. Mol Cell. 2003. PMID: 12667444 Free article.

8

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production.

Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ, Kastner DL. Chae JJ, et al. Among authors: kastner dl. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9982-7. doi: 10.1073/pnas.0602081103. Epub 2006 Jun 19. Proc Natl Acad Sci U S A. 2006. PMID: 16785446 Free PMC article.

9

The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment.

Chae JJ, Wood G, Richard K, Jaffe H, Colburn NT, Masters SL, Gumucio DL, Shoham NG, Kastner DL. Chae JJ, et al. Among authors: kastner dl. Blood. 2008 Sep 1;112(5):1794-803. doi: 10.1182/blood-2008-01-134932. Epub 2008 Jun 24. Blood. 2008. PMID: 18577712 Free PMC article.

10

Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy.

Chae JJ, Aksentijevich I, Kastner DL. Chae JJ, et al. Among authors: kastner dl. Br J Haematol. 2009 Sep;146(5):467-78. doi: 10.1111/j.1365-2141.2009.07733.x. Epub 2009 May 14. Br J Haematol. 2009. PMID: 19466978 Free PMC article. Review.

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