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BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors.
Rigby M, Bennett G, Chen L, Mudd GE, Harrison H, Beswick PJ, Van Rietschoten K, Watcham SM, Scott HS, Brown AN, Park PU, Campbell C, Haines E, Lahdenranta J, Skynner MJ, Jeffrey P, Keen N, Lee K. Rigby M, et al. Among authors: beswick pj. Mol Cancer Ther. 2022 Dec 2;21(12):1747-1756. doi: 10.1158/1535-7163.MCT-21-0875. Mol Cancer Ther. 2022. PMID: 36112771 Free PMC article.
An Assay for Periplasm Entry Advances the Development of Chimeric Peptide Antibiotics.
Wagstaff JM, Balmforth M, Lewis N, Dods R, Rowland C, van Rietschoten K, Chen L, Harrison H, Skynner MJ, Dawson M, Ivanova-Berndt G, Beswick P. Wagstaff JM, et al. Among authors: beswick p. ACS Infect Dis. 2020 Sep 11;6(9):2355-2361. doi: 10.1021/acsinfecdis.0c00389. Epub 2020 Aug 15. ACS Infect Dis. 2020. PMID: 32697574
Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor.
Abdi MH, Beswick PJ, Billinton A, Chambers LJ, Charlton A, Collins SD, Collis KL, Dean DK, Fonfria E, Gleave RJ, Lejeune CL, Livermore DG, Medhurst SJ, Michel AD, Moses AP, Page L, Patel S, Roman SA, Senger S, Slingsby B, Steadman JG, Stevens AJ, Walter DS. Abdi MH, et al. Among authors: beswick pj. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5080-4. doi: 10.1016/j.bmcl.2010.07.033. Epub 2010 Jul 14. Bioorg Med Chem Lett. 2010. PMID: 20673717
Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor.
Chambers LJ, Stevens AJ, Moses AP, Michel AD, Walter DS, Davies DJ, Livermore DG, Fonfria E, Demont EH, Vimal M, Theobald PJ, Beswick PJ, Gleave RJ, Roman SA, Senger S. Chambers LJ, et al. Among authors: beswick pj. Bioorg Med Chem Lett. 2010 May 15;20(10):3161-4. doi: 10.1016/j.bmcl.2010.03.096. Epub 2010 Mar 30. Bioorg Med Chem Lett. 2010. PMID: 20399651
What does the aromatic ring number mean for drug design?
Ward SE, Beswick P. Ward SE, et al. Among authors: beswick p. Expert Opin Drug Discov. 2014 Sep;9(9):995-1003. doi: 10.1517/17460441.2014.932346. Epub 2014 Jun 23. Expert Opin Drug Discov. 2014. PMID: 24955724 Review.
60 results